Could a bladder rinse stop UTIs before they start?

NCT ID NCT06332781

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether putting the antibiotic gentamicin directly into the bladder can prevent recurrent urinary tract infections (UTIs) in postmenopausal women. Twenty women were split into two groups: one received gentamicin via a catheter into the bladder, and the other took a daily oral antibiotic pill. The main goal was to see if this approach is practical and acceptable, not yet to prove it works better than standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gentamicin (given directly into the bladder)

What this could lead to

If this approach works, it could offer an alternative way to prevent recurrent UTIs without taking daily oral antibiotics.

What could go wrong

This was a very small feasibility study with only 20 participants, so results may not apply to everyone. The treatment involves a procedure to put medication into the bladder, which may be less convenient than taking a pill.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial urinary tract infection urinary tract infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Women & Infants Hospital

    Providence, Rhode Island, 02903, United States