Could a bladder rinse stop UTIs before they start?
NCT ID NCT06332781
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether putting the antibiotic gentamicin directly into the bladder can prevent recurrent urinary tract infections (UTIs) in postmenopausal women. Twenty women were split into two groups: one received gentamicin via a catheter into the bladder, and the other took a daily oral antibiotic pill. The main goal was to see if this approach is practical and acceptable, not yet to prove it works better than standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gentamicin (given directly into the bladder)
- What this could lead to
- If this approach works, it could offer an alternative way to prevent recurrent UTIs without taking daily oral antibiotics.
- What could go wrong
- This was a very small feasibility study with only 20 participants, so results may not apply to everyone. The treatment involves a procedure to put medication into the bladder, which may be less convenient than taking a pill.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Women & Infants Hospital
Providence, Rhode Island, 02903, United States
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