New drug combo takes on tough lung cancer

NCT ID NCT07550842

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new drug called BL0020 combined with the immunotherapy Toripalimab in 33 people whose extensive-stage small cell lung cancer has returned after initial treatment. The main goal is to check safety and find the right dose, while also seeing if the combination can shrink tumors. It is an open-label study, meaning everyone gets the active treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BL0020 (a drug) combined with Toripalimab (an immunotherapy)

What this could lead to

If it works, this could point toward a new treatment option for people with recurrent extensive-stage small cell lung cancer.

What could go wrong

This is a very early Phase 1 trial with only 33 participants, so it is primarily testing safety. The combination may not shrink tumors or improve survival, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, 150081, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450008, China

  • Shanghai Chest Hospital

    Shanghai, 200030, China

  • Shanghai Pulmonary Hospital

    Shanghai, 200433, China

  • Taizhou Hospital of Zhejiang Province

    Taizhou, Zhejiang, 317000, China

  • The First Hospital of China Medical University

    Shenyang, Liaoning, 110001, China

  • The First People's Hospital of Changzhou

    Changzhou, Jiangsu, 213003, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, Hubei, 430030, China