New drug shows promise for calming bipolar mania in hospitalized patients

NCT ID NCT06419582

Summary

This study tested whether an experimental drug called BHV-7000 could safely and effectively treat acute manic episodes in people with bipolar I disorder. Researchers enrolled 274 hospitalized patients and compared BHV-7000 against a placebo over 21 days, measuring changes in manic symptoms. The goal was to see if this new treatment could reduce the severity of manic episodes more effectively than no active medication.

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Contacts and locations

Locations

  • Advanced Research Center, Inc.

    Anaheim, California, 92805, United States

  • Arch Clinical Trials

    St Louis, Missouri, 63141, United States

  • Atlanta Center for Medical Research

    Atlanta, Georgia, 30331, United States

  • CBH Health

    Gaithersburg, Maryland, 20877, United States

  • CIT IE

    Riverside, California, 92506, United States

  • CIT LA

    Bellflower, California, 90706, United States

  • CenExel iResearch, LLC

    Decatur, Georgia, 30030, United States

  • CenExel iResearch, LLC

    Savannah, Georgia, 31405, United States

  • Cenexel - RCA

    Hollywood, Florida, 33024, United States

  • Cenexel CNS

    Garden Grove, California, 92845, United States

  • Cenexel CNS

    Torrance, California, 90504, United States

  • Community Clinical Research, Inc.

    Austin, Texas, 78754, United States

  • Floridian Neuroscience Institute

    Miami Lakes, Florida, 33016, United States

  • Hassman Research Institute

    Marlton, New Jersey, 08053, United States

  • InSite Clinical Research, LLC

    DeSoto, Texas, 75115, United States

  • LCC Medical Research Inst

    Miami, Florida, 33126, United States

  • Midwest Clinical Research Center

    Dayton, Ohio, 45417, United States

  • NBCR

    North Canton, Ohio, 44720, United States

  • NRC Research Institute

    Orange, California, 92868, United States

  • Neuroscience Research Institute

    West Palm Beach, Florida, 33407, United States

  • Pillar Clinical Research

    Chicago, Illinois, 60641, United States

  • Pillar Clinical Research, LLC

    Bentonville, Arkansas, 72712, United States

  • Pillar Clinical Research, LLC

    Richardson, Texas, 75080, United States

  • Precise Clinical Research

    Flowood, Mississippi, 39232, United States

  • ProScience Research Group

    Culver City, California, 90230, United States

  • RBA

    Staten Island, New York, 10329, United States

  • Segal Trials - Larkin Behavioral Health Services-Inpatient & Early Phase Site

    Hollywood, Florida, 33021, United States

  • Segal Trials - Miami Lakes Medical Research-Inpatient & Early Phase Site

    Miami Lakes, Florida, 33016, United States

  • Synergy San Diego

    Lemon Grove, California, 91945, United States

  • Uptown Research Institute

    Chicago, Illinois, 60640, United States

  • WIRG

    Little Rock, Arkansas, 72211, United States

  • WRN

    Rogers, Arkansas, 72758, United States

Conditions

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