New hope for bipolar depression? major trial tests promising drug

NCT ID NCT02600494

Completed Disease control Sponsor: Intra-Cellular Therapies, Inc. Source: ClinicalTrials.gov ↗

Summary

This large, completed study tested whether a medication called ITI-007 (lumateperone) could safely help reduce depressive symptoms in adults with bipolar disorder. Over 550 participants with bipolar I or II disorder who were experiencing a major depressive episode were randomly assigned to receive either the study drug or a placebo for six weeks. The main goal was to see if the drug led to a greater improvement in depression scores compared to the placebo.

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Contacts and locations

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Locations

Clinical Site

Little Rock, Arkansas, United States
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Rogers, Arkansas, United States
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Cerritos, California, United States
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Culver City, California, United States
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Garden Grove, California, United States
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Lemon Grove, California, United States
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National City, California, United States
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Oakland, California, United States
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Oceanside, California, United States
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Orange, California, United States
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Pico Rivera, California, United States
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Riverside, California, United States
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San Diego, California, United States
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San Marcos, California, United States
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Santa Rosa, California, United States
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Colorado Springs, Colorado, United States
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Bradenton, Florida, United States
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Fort Myers, Florida, United States
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Jacksonville, Florida, United States
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Lauderhill, Florida, United States
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Miami, Florida, United States
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North Miami, Florida, United States
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Orlando, Florida, United States
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Atlanta, Georgia, United States
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Chicago, Illinois, United States
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Hoffman Estates, Illinois, United States
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Lake Charles, Louisiana, United States
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Baltimore, Maryland, United States
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Boston, Massachusetts, United States
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O'Fallon, Missouri, United States
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St Louis, Missouri, United States
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Las Vegas, Nevada, United States
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Berlin, New Jersey, United States
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Cherry Hill, New Jersey, United States
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Marlton, New Jersey, United States
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Toms River, New Jersey, United States
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Brooklyn, New York, United States
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Cedarhurst, New York, United States
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New York, New York, United States
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Rochester, New York, United States
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Staten Island, New York, United States
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Cincinnati, Ohio, United States
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Cleveland, Ohio, United States
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Dayton, Ohio, United States
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Garfield Heights, Ohio, United States
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Oklahoma City, Oklahoma, United States
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Allentown, Pennsylvania, United States
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Norristown, Pennsylvania, United States
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Philadelphia, Pennsylvania, United States
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Memphis, Tennessee, United States
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Austin, Texas, United States
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Dallas, Texas, United States
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Houston, Texas, United States
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Petersburg, Virginia, United States
Clinical Site

Everett, Washington, United States

Conditions

Explore the condition pages connected to this study.

BIPOLAR DEPRESSION