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Cheaper cancer drug alternative under Real-World scrutiny

NCT ID NCT06808685

Recruiting now Disease control Sponsor: Libbs Farmacêutica LTDA Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is tracking how well a biosimilar drug called Elovie (a copy of bevacizumab) works for people with advanced colorectal cancer that cannot be removed by surgery. Researchers will follow 133 patients in Brazil who are receiving Elovie as their first treatment, measuring how long they stay on the drug before needing a switch and how long they live. The goal is to see if this more affordable option performs as expected in real-world hospital settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bevacizumab biosimilar (Elovie)
What this could lead to
If successful, this study could confirm that Elovie works as well as the original bevacizumab for treating metastatic colorectal cancer in everyday clinical practice.
What could go wrong
This is an observational study, not a controlled trial, so results may be less definitive. It is also limited to the Brazilian population, so findings may not apply elsewhere.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC COLORECTAL CANCER

Contacts and locations

Locations

  • Associação Hospitalar Moinhos de Vento

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90560-032, Brazil

  • CEON+ Pesquisas

    RECRUITING

    São Caetano do Sul, São Paulo, 09541-270, Brazil

  • COE Ensino e Pesquisa

    RECRUITING

    São José dos Campos, São Paulo, 12243-580, Brazil

  • Centro Paulista de Oncologia

    RECRUITING

    São Paulo, São Paulo, 04.538-135, Brazil

  • Centro de Ensino e Pesquisa - Hospital São Marcos

    RECRUITING

    Teresina, Piauí, 64002-595, Brazil

  • Centro de Oncologia do Paraná (COP)

    RECRUITING

    Curitiba, Paraná, 82305-100, Brazil

  • Centro de Pesquisa Unimed Londrina

    RECRUITING

    Londrina, Paraná, 86050-460, Brazil

  • Centro de Pesquisa Unimed Porto Alegre

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90560-003, Brazil

  • Hospital Vera Cruz

    RECRUITING

    Campinas, São Paulo, 13092-108, Brazil

  • Instituto Dor de Pesquisa E Ensino

    RECRUITING

    Recife, Pernambuco, 50070-480, Brazil

  • Instituto Dor de Pesquisa E Ensino

    RECRUITING

    São Paulo, São Paulo, Brazil

  • OncoJaraguá

    RECRUITING

    Jaraguá do Sul, Santa Catarina, 89253-080, Brazil

  • Unidade de Ensino e Pesquisa UEP-COHM

    RECRUITING

    Santo Ângelo, Rio Grande do Sul, 98.801.706, Brazil

  • Unimed Vitória

    RECRUITING

    Vitória, Espírito Santo, 29047660, Brazil

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