Dissolvable scaffold could save legs from amputation

NCT ID NCT06071429

First seen Feb 06, 2026 · Last updated May 13, 2026 · Updated 16 times

Summary

This study tests a new device called the MAGNITUDE BRS System, a dissolvable scaffold that releases medicine to keep leg arteries open. It is for people with chronic limb-threatening ischemia, a severe condition where blocked arteries in the leg can lead to amputation. About 300 participants will be randomly assigned to get this scaffold or a standard treatment. The goal is to see if the scaffold helps save the limb and keeps the artery open longer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CUMC/NYP

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Staten Island University Hospital - Northwell Health

    RECRUITING

    Staten Island, New York, 10305, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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