Bionic pancreas could simplify diabetes care for cystic fibrosis patients
NCT ID NCT06449677
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a device called the iLet Bionic Pancreas, which automatically adjusts insulin delivery based on continuous glucose monitor readings, in people with cystic fibrosis-related diabetes. About 150 participants aged 14 and older will either use the bionic pancreas or their usual insulin method for 13 weeks, then all will use the bionic pancreas for another 13 weeks. The goal is to see if the automated system improves time spent in healthy blood sugar range compared to standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- iLet Bionic Pancreas System (automated insulin delivery device)
- What this could lead to
- If successful, this could provide a simpler, more effective way to manage blood sugar in cystic fibrosis-related diabetes, reducing the burden of daily insulin adjustments.
- What could go wrong
- This is a relatively small phase 3 trial (150 people) and results may not apply to all patients. The device may not work as well in real-world settings or could have technical issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
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Children's Hospital of Philadelphia
COMPLETEDPhiladelphia, Pennsylvania, 19104, United States
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Children's Mercy Hospital
RECRUITINGKansas City, Missouri, 64108, United States
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30329, United States
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Indiana University School of Medicine
RECRUITINGIndianapolis, Indiana, 46202, United States
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Johns Hopkins University School of Medicine
RECRUITINGBaltimore, Maryland, 21287, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75235, United States
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University Hospitals of Cleveland
RECRUITINGCleveland, Ohio, 44106, United States
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University of Colorado-Barbara Davis Center for Diabetes
RECRUITINGAurora, Colorado, 80045, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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University of Texas Health San Antonio
RECRUITINGSan Antonio, Texas, 78207, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84132, United States
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University of Virginia-Center for Diabetes Technology
RECRUITINGCharlottesville, Virginia, 22903, United States
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Yale University School of Medicine
RECRUITINGNew Haven, Connecticut, 06511, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood pressure drug may help preserve insulin in cystic fibrosis
- Sugar showdown: could cutting sweets curb CF diabetes?
- Could a weekly shot delay diabetes in cystic fibrosis? new trial launches
- Blood test tracks diabetes risk in cystic fibrosis patients
- Cystic fibrosis diabetes gene hunt: 1,500 patients sought
- Can a simple sensor replace finger pricks for kids in the hospital?