Blood test may guide depression treatment
NCT ID NCT07269886
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looked at whether giving doctors extra information from a blood test and genetics could help them choose better medications for people with depression. 79 adults with moderate to severe depression took part. Half of the doctors received this extra information, while the other half provided standard care. The study measured how much depression symptoms improved after 8 weeks.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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79 people
The number who actually took part.
- Started
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Aug 2022
- Finished
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Jun 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Urban depressive outpatients from the City of Buenos Aires were recruited. The population of Buenos Aires is predominantly of Caucasian origin, mainly with ancestry from Italy and Spain.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Being male or female, aged 18-65. 2. Having a current DSM-5 diagnosis of non-psychotic Major Depressive Disorder confirmed by SCID. 3. Having moderate to severe depressive symptoms as measured by the HAM-D-17. 4. Being indicated for pharmacotherapy for Major Depressive Disorder. 5. Providing written informed consent (signed and dated). \- Exclusion Criteria: 1. Having a current or past diagnosis of bipolar disorder or psychotic disorders. 2. Having a moderate to severe substance use disorder within the past six months. 3. Having active suicidal ideation. 4. Having a neurocognitive disorder. 5. Having an unstable or decompensated medical illness likely to confound study outcomes. 6. Being pregnant or lactating. 7. Having known contraindications to the indicated antidepressant classes. 8. Being unable to provide informed consent. \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Neomente
Buenos Aires, 1425, Argentina
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Other studies related to the condition(s) this trial covers.
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