Scientists hunt for clues to better colorectal cancer treatment

NCT ID NCT01822444

First seen Apr 21, 2026 · Last updated Apr 30, 2026 · Updated 2 times

Summary

This study looked at 76 adults with advanced colorectal cancer that has a specific gene change (mutant K-ras). The goal was to find biological markers that can predict how well a combination of chemotherapy (FOLFOX) and the drug bevacizumab works. Researchers measured tumor response and survival times to identify which patients benefit most from this treatment.

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Contacts and locations

Locations

  • Beaumont Hospital

    Dublin, Ireland

  • Bon Secours Hospital

    Cork, Ireland

  • Cork University Hospital

    Cork, Ireland

  • Galway University Hospital

    Galway, Ireland

  • Gemeinschaftspraxis Haematologie/Onkologie

    Lebach, Germany

  • Kilnikum Ludwigsburg

    Ludwigsburg, Germany

  • Medizinische Klinik III, Universitaetsklinikum

    Aachen, Germany

  • Medizinische Klinik and Poliklinik Mainz

    Mainz, Germany

  • Onkologisches Zentrum

    Deggendorf, Germany

  • Private Practice Oncology

    Speyer, Rhineland-Palatinate, Germany

  • Sligo General Hospital

    Sligo, Ireland

  • St James Hospital

    Dublin, Ireland

  • St Vincent's University Hospital

    Dublin, D4, Ireland

  • The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital

    Dublin, Ireland

  • Univeritaetsmedizin Mannheim

    Mannheim, Germany

  • University Hospital Saarland

    Homburg, Germany

  • Waterford Regional Hospital

    Waterford, Ireland

Conditions

Explore the condition pages connected to this study.