Blood Test-Guided antibiotic could stop pneumonia from turning deadly

NCT ID NCT06294600

First seen Jan 08, 2026 · Last updated May 14, 2026 · Updated 22 times

Summary

This study tests whether giving the antibiotic clarithromycin early, based on a blood test result, can prevent pneumonia from worsening into sepsis. About 330 adults with community-acquired pneumonia who are at risk will receive either clarithromycin or a placebo. The goal is to see if this approach improves symptoms, organ function, and immune markers within a few days.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 1st Department of Internal Medicine - General Hospital of Athens "Sismanogleio-Amalia Fleming"

    NOT_YET_RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 1st Department of Internal Medicine, AHEPA University General Hospital of Thessaloniki

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 1st Department of Internal Medicine, EVANGELISMOS Athens General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 1st Department of Internal Medicine, G. GENNIMATAS Athens General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 1st Department of Internal Medicine, General University Hospital of Ioannina

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 1st Department of Internal Medicine, KORGIALENEIO-BENAKEIO E.E.S. Athens General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 1st Department of Internal Medicine, THRIASIO General Hospital of Elefsis

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 1st University Department of Pulmonary Medicine, SOTIRIA General Hospital of Chest Diseases of Athens

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 2nd Department of Internal Medicine, Attikon University Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 2nd Department of Internal Medicine, THRIASIO General Hospital of Elefsis

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 2nd Department of Internal Medicine, TZANEIO Piraeus General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 2nd Department of Internal Medicine, University General Hospital of Alexandroupolis

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 3rd Department of Internal Medicine - General State Hospital of Nikaia "Saint Panteleimon" - West Attica General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 3rd Department of Internal Medicine, General Hospital of Athens KORGIALENEIO- BENAKEIO E.E.S.

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 3rd Department of Internal Medicine, PAPAGEORGIOU General Hospital of Thessaloniki

    RECRUITING

    Thessaloniki, Thessaloniki, 564 29, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 3rd University Department of Internal Medicine, SOTIRIA Athens General Hospital of Chest Diseases

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 4th Department of Internal Medicine, Attikon University Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 5th Pulmonary Department, SOTIRIA Athens General Hospital of Chest Diseases

    RECRUITING

    Athens, Athens, 115 27, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 6th Pulmonary Medicine Department, SOTIRIA General Hospital of Chest Diseases of Athens

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Chest Medicine, EVANGELISMOS Athens General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Internal Medicine, Larissa University General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Internal Medicine, Patras University General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Pulmonary Medicine, General Hospital of Kerkira

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emergency Department, TZANEIO Piraeus General Hospital

    RECRUITING

    Athens, Greece, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.