New mesh may reduce infections in complex hernia surgery
NCT ID NCT01594450
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether using a biological mesh (made from human or animal tissue) during surgery for infected ventral hernias leads to fewer wound problems than standard wound care alone. About 110 adults with infected hernias were randomly assigned to receive either the mesh or standard treatment. Researchers tracked infections, hernia recurrence, pain, and quality of life for up to three years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
biological mesh (acellular dermal matrix)
What this could lead to
If successful, using a biological mesh could lower infection and hernia recurrence rates after surgery for infected ventral hernias.
What could go wrong
This is a completed Phase 3 trial with 110 participants, so results are available but may not apply to all hernia types. Biological meshes are expensive and may not outperform standard care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Claude Huriez Hospital, University hospital
Lille, 59037, France