Can a dissolving heart valve spare kids from repeat surgeries?

NCT ID NCT03022708

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial is testing a new type of heart valve made from a material that the body absorbs over time. It is designed for children and young adults who need surgery to fix a congenital heart defect affecting the passage from the heart to the lungs. The valve is implanted during surgery to help blood flow properly. The study aims to see if this valve is safe and works well, potentially reducing the need for future operations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Xeltis Bioabsorbable Pulmonary Valved Conduit
What this could lead to
If successful, this could offer a safer, more durable option for repairing heart defects, potentially reducing the need for repeat surgeries.
What could go wrong
This is a small, early-stage study with only 6 participants, so results may not apply broadly. The device could fail or cause complications, requiring additional procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Pittsburgh of UPMC (Xplore1)

    Pittsburgh, Pennsylvania, 15224, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Institut Jantung Negara Sdn Bhd

    Kuala Lumpur, Malaysia

  • Joe DiMaggio Children's Hospital

    Hollywood, Florida, 33021, United States

  • Multiprofile Hospital for Active Treatment "National cardiology hospital" EAD, Department of Congenital Heart Defects Surgery

    Sofia, Bulgaria

  • New York Presbyterian Hospital - Columbia University (Xplore1)

    New York, New York, 10032, United States

  • UTSW- Dallas Children's Hospital

    Dallas, Texas, 75390-8835, United States

  • University Children's Hospital of Cracow

    Krakow, Poland

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