Brain zaps for depression: new hope or hype?
NCT ID NCT04392947
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 31 times
Summary
This study tested whether a non-invasive brain stimulation method called theta burst stimulation (TBS) can help people with major depression who haven't responded well to standard treatments. 238 adults with moderate to severe depression received either real TBS or a sham (fake) treatment daily for six weeks, alongside their usual medication or therapy. The goal was to see if TBS could reduce depression symptoms more than the sham treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Bezirkskrankenhaus Augsburg
Augsburg, 86156, Germany
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University of Leipzig, Dept. Psychiatry and Psychotherapy
Leipzig, Germany
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University of Munich
Munich, 80336, Germany
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University of Regensburg, Dept. Psychiatry and Psychotherapy
Regensburg, 93053, Germany
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University of Tuebingen, Dept Psychiatry and Psychotherapy
Tübingen, 72076, Germany
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University of Um, Dept. Psychiatry and Psychotherapy
Ulm, 89075, Germany
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University of Wuerzburg, Dept. Psychiatry and Psychotherapy
Würzburg, Germany
Conditions
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