Global hunt for genetic clues to common heart valve defect

NCT ID NCT01980797

Summary

This large, long-term study aims to discover the genetic causes of bicuspid aortic valve disease and understand why it leads to serious heart complications in some people. Researchers are collecting health data and genetic information from over 6,000 patients worldwide to track the disease's natural course. The study does not test any treatments; it focuses on gathering knowledge to help predict risks and guide future care.

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Contacts and locations

Locations

  • Boston Medical Center

    Boston, Massachusetts, 02218, United States

  • Hospital Vall d'Hebron

    Barcelona, 08035, Spain

  • Istituto Policlinico San Donato

    San Donato Milanese, Milan, 20097, Italy

  • Laval University

    Québec, Quebec, G1V 4G5, Canada

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Monaldi Hospital

    Naples, 80100, Italy

  • Second University of Naples

    Naples, 80131, Italy

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Oxford

    Oxford, OX3 9DU, United Kingdom

  • University of Salerno

    Salerno, 36-83023, Italy

  • University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.