Bicarbonate drink could reduce emergency C-Sections in prolonged labour

NCT ID NCT07321379

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether a single dose of oral bicarbonate can reduce the need for assisted delivery (emergency C-section or vacuum/forceps) in first-time mothers with prolonged labour. 1520 women will be randomly assigned to receive bicarbonate or a placebo. After two hours, if labour hasn't progressed, standard oxytocin treatment is given. The study also tracks birth experience and newborn health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sodium bicarbonate
What this could lead to
If it works, this could offer a simple, low-cost way to reduce emergency C-sections and vacuum/forceps deliveries in prolonged labour.
What could go wrong
This is an early-stage trial with no prior human data for this use. The effect may be small or none, and results may not apply to all women.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, 8200, Denmark

  • Copenhagen University Hospital, Hvidovre

    Copenhagen, Denmark

  • Copenhagen University Hospital, Rigshospitalet

    Copenhagen, Denmark

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