New drug trial aims to improve lung function in fibrosis patients
NCT ID NCT07036523
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new medicine called BI 765423 in 71 adults with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring and breathing problems. Participants receive either the drug or a placebo by infusion every four weeks for about 3 months. The main goal is to see if the drug improves lung capacity, measured by forced vital capacity (FVC), compared to placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BI 765423
What this could lead to
If it works, this could point toward a new treatment to slow lung damage in people with idiopathic pulmonary fibrosis.
What could go wrong
This is an early Phase IIa trial with only 71 participants, so results may not confirm benefit. The drug may cause side effects or fail to improve lung function compared to placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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A. O. Universitaria Careggi
NOT_YET_RECRUITINGFlorence, 50137, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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ASST Papa Giovanni XXIII
NOT_YET_RECRUITINGBergamo, 24127, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino
RECRUITINGTorino, 10126, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Ospedaliera dei Colli
NOT_YET_RECRUITINGNaples, 80131, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cantonal Hospital of Aarau
RECRUITINGAarau, 5001, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Hospitalier de l'Universite de Montreal (CHUM)
RECRUITINGMontreal, Quebec, H2X 0A9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clinical Trials Center of Middle Tennessee, LLC
RECRUITINGFranklin, Tennessee, 37067, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cliniques Universitaires Saint-Luc
NOT_YET_RECRUITINGBrussels, 1200, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia University Medical Center-New York Presbyterian Hospital
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke University Medical Center
NOT_YET_RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITINGRoma, 00168, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hamamatsu University Hospital
RECRUITINGShizuoka, Hamamatsu, 431-3192, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitari de Bellvitge
RECRUITINGL Hospitalet Del Llobregat, 08907, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario De La Princesa
RECRUITINGMadrid, 08035, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Vall Hebron
RECRUITINGBarcelona, 08035, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Virgen del Rocío
NOT_YET_RECRUITINGSeville, 41013, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Inje University Haeundae Paik Hospital
RECRUITINGBusan, 48108, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institute for Respiratory Health
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kanagawa Cardiovascular and Respiratory Center
RECRUITINGKanagawa, Yokohama, 236-0051, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kelowna Respirology & Allergy Research
RECRUITINGKelowna, British Columbia, V1Y 3H5, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Medizinische Hochschule Hannover
RECRUITINGHanover, 30625, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Monash Health
RECRUITINGClayton, Victoria, 3168, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Hospital Organization Kinki-Chuo Chest Medical Center
RECRUITINGOsaka, Sakai, 591-8555, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Hospital Organization Kyushu Medical Center
RECRUITINGFukuoka, Fukuoka, 810-8563, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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QEII Health Sciences Centre
RECRUITINGHalifax, Nova Scotia, B3H 3A7, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renstar Medical Research
RECRUITINGOcala, Florida, 34470, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH
RECRUITINGEssen, 45239, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Soon Chun Hyang University Hospital Bucheon
RECRUITINGBucheon-si, Gyeonggi-do, 14584, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Soonchunhyang University Hospital Seoul
RECRUITINGSeoul, 04401, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Synergy Respiratory Care
RECRUITINGSherwood Park, Alberta, T8H 0N2, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Temple University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Lung Research Center, LLC
RECRUITINGChesterfield, Missouri, 63017, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Prince Charles Hospital
RECRUITINGChermside, Queensland, 4032, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tosei General Hospital
NOT_YET_RECRUITINGAichi, Seto, 489-8642, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Cincinnati Medical Center
NOT_YET_RECRUITINGCincinnati, Ohio, 45267, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida
NOT_YET_RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Fukui Hospital
RECRUITINGFukui, Yoshida-gun, 910-1193, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Iowa Hospitals and Clinics
NOT_YET_RECRUITINGIowa City, Iowa, 52242, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Medical Center
NOT_YET_RECRUITINGKansas City, Kansas, 66103-2937, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Minnesota
NOT_YET_RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Missouri Health System
NOT_YET_RECRUITINGColumbia, Missouri, 65212, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Virginia Health System
NOT_YET_RECRUITINGCharlottesville, Virginia, 22903, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitätsspital Basel
RECRUITINGBasel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Weill Cornell Medical College
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yvoir - UNIV UCL de Mont-Godinne
NOT_YET_RECRUITINGYvoir, 5530, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••