New drug trial aims to improve lung function in fibrosis patients

NCT ID NCT07036523

Recruiting now Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study tests a new medicine called BI 765423 in 71 adults with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring and breathing problems. Participants receive either the drug or a placebo by infusion every four weeks for about 3 months. The main goal is to see if the drug improves lung capacity, measured by forced vital capacity (FVC), compared to placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BI 765423
What this could lead to: If it works, this could point toward a new treatment to slow lung damage in people with idiopathic pulmonary fibrosis.
What could go wrong: This is an early Phase IIa trial with only 71 participants, so results may not confirm benefit. The drug may cause side effects or fail to improve lung function compared to placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

idiopathic pulmonary fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IDIOPATHIC PULMONARY FIBROSIS

Contacts and locations

Locations

A. O. Universitaria Careggi
RECRUITING

Florence, 50137, Italy
ASST Papa Giovanni XXIII
RECRUITING

Bergamo, 24127, Italy
Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino
RECRUITING

Torino, 10126, Italy
Azienda Ospedaliera dei Colli
RECRUITING

Naples, 80131, Italy
Cantonal Hospital of Aarau
RECRUITING

Aarau, 5001, Switzerland
Centre Hospitalier de l'Universite de Montreal (CHUM)
RECRUITING

Montreal, Quebec, H2X 0A9, Canada
Clinical Trials Center of Middle Tennessee, LLC
RECRUITING

Franklin, Tennessee, 37067, United States
Cliniques Universitaires Saint-Luc
RECRUITING

Brussels, 1200, Belgium
Columbia University Medical Center-New York Presbyterian Hospital
RECRUITING

New York, New York, 10032, United States
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Roma, 00168, Italy
Hamamatsu University Hospital
RECRUITING

Shizuoka, Hamamatsu, 431-3192, Japan
Hospital Universitari de Bellvitge
RECRUITING

L Hospitalet Del Llobregat, 08907, Spain
Hospital Universitario De La Princesa
RECRUITING

Madrid, 08035, Spain
Hospital Vall Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Virgen del Rocío
RECRUITING

Seville, 41013, Spain
Inje University Haeundae Paik Hospital
RECRUITING

Busan, 48108, South Korea
Institute for Respiratory Health
RECRUITING

Nedlands, Western Australia, 6009, Australia
Kanagawa Cardiovascular and Respiratory Center
RECRUITING

Kanagawa, Yokohama, 236-0051, Japan
Kelowna Respirology & Allergy Research
RECRUITING

Kelowna, British Columbia, V1Y 3H5, Canada
Medizinische Hochschule Hannover
RECRUITING

Hanover, 30625, Germany
Monash Health
RECRUITING

Clayton, Victoria, 3168, Australia
National Hospital Organization Kinki-Chuo Chest Medical Center
RECRUITING

Osaka, Sakai, 591-8555, Japan
National Hospital Organization Kyushu Medical Center
RECRUITING

Fukuoka, Fukuoka, 810-8563, Japan
QEII Health Sciences Centre
RECRUITING

Halifax, Nova Scotia, B3H 3A7, Canada
Renstar Medical Research
RECRUITING

Ocala, Florida, 34470, United States
Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH
RECRUITING

Essen, 45239, Germany
Soon Chun Hyang University Hospital Bucheon
RECRUITING

Bucheon-si, Gyeonggi-do, 14584, South Korea
Soonchunhyang University Hospital Seoul
RECRUITING

Seoul, 04401, South Korea
Synergy Respiratory Care
RECRUITING

Sherwood Park, Alberta, T8H 0N2, Canada
Temple University
RECRUITING

Philadelphia, Pennsylvania, 19140, United States
The Lung Research Center, LLC
RECRUITING

Chesterfield, Missouri, 63017, United States
The Prince Charles Hospital
RECRUITING

Chermside, Queensland, 4032, Australia
Tosei General Hospital
RECRUITING

Aichi, Seto, 489-8642, Japan
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States
University of Cincinnati Medical Center
NOT_YET_RECRUITING

Cincinnati, Ohio, 45267, United States
University of Florida
RECRUITING

Gainesville, Florida, 32610, United States
University of Fukui Hospital
RECRUITING

Fukui, Yoshida-gun, 910-1193, Japan
University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66103-2937, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Missouri Health System
RECRUITING

Columbia, Missouri, 65212, United States
University of Virginia Health System
NOT_YET_RECRUITING

Charlottesville, Virginia, 22903, United States
Universitätsspital Basel
RECRUITING

Basel, 4031, Switzerland
Weill Cornell Medical College
RECRUITING

New York, New York, 10065, United States
Yvoir - UNIV UCL de Mont-Godinne
RECRUITING

Yvoir, 5530, Belgium

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