New drug combo shows promise for ulcerative colitis sufferers

NCT ID NCT03123120

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 25 times

Summary

This study tested an experimental drug called BI 655130 in 22 adults with mild-to-moderate ulcerative colitis who were already taking TNF inhibitor therapy. The goal was to see if adding BI 655130 could help heal the lining of the colon (mucosal healing) and improve symptoms. The trial focused on safety and early signs of effectiveness, with results measured at 12 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aalborg Sygehus Syd

    Aalborg, 9100, Denmark

  • Akershus Universitetssykehus HF

    Lørenskog, N-1478, Norway

  • Amsterdam UMC, Locatie AMC

    Amsterdam, 1105 AZ, Netherlands

  • Guy's Hospital

    London, SE1 9RT, United Kingdom

  • Hospital Politècnic La Fe

    Valencia, 46026, Spain

  • Hospital Puerta de Hierro

    Majadahonda, 28222, Spain

  • Hospital Universitario Marqués de Valdecilla

    Santander, 39008, Spain

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • Odense University Hospital

    Odense, 5000, Denmark

  • Sanos Clinic

    Herlev, 2730, Denmark

  • St James's University Hospital

    Leeds, LS9 7TF, United Kingdom

  • Universitätsklinikum Erlangen

    Erlangen, 91054, Germany

  • Universitätsklinikum Freiburg

    Freiburg im Breisgau, 79106, Germany

  • Universitätsklinikum Schleswig-Holstein, Campus Kiel

    Kiel, 24105, Germany

  • Universitätsklinikum Ulm

    Ulm, 89081, Germany

  • Whiston Hospital

    Prescot, L35 5DR, United Kingdom

Conditions

Explore the condition pages connected to this study.