New drug hopes to shrink tumors in patients out of options
NCT ID NCT07306559
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new drug called BI 3820768 in adults with advanced germ cell tumors, endometrial cancer, or ovarian cancer who have run out of treatment options. The drug aims to help the immune system fight cancer. Researchers will give increasing doses to find a safe amount that may shrink tumors. Participants receive weekly injections for 6 weeks, then every 3 weeks, and are followed for up to 3 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BI 3820768
What this could lead to
If this works, it could point toward a new treatment option for people with advanced cancers that have not responded to other therapies.
What could go wrong
This is a very early Phase 1 trial, so the drug may not work or may cause serious side effects. It is the first time this drug is tested in humans, so success is uncertain.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cliniques Universitaires Saint-Luc
NOT_YET_RECRUITINGBrussels, 1200, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clínica Universidad de Navarra - Madrid
NOT_YET_RECRUITINGMadrid, 28027, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitari Vall d'Hebron
NOT_YET_RECRUITINGBarcelona, 08035, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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INS Paoli-Calmettes
RECRUITINGMarseille, 13009, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Indiana University
NOT_YET_RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Gustave Roussy
NOT_YET_RECRUITINGVillejuif, 94800, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Japanese Foundation for Cancer Research
RECRUITINGTokyo, Koto-ku, 135-8550, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Klinikum der Universität München AÖR
RECRUITINGMünchen, 81377, Germany
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National Cancer Center Hospital East
NOT_YET_RECRUITINGChiba, Kashiwa, 277-8577, Japan
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Texas MD Anderson Cancer Center
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UZ Leuven
SUSPENDEDLeuven, 3000, Belgium
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Universitätsklinikum Würzburg AÖR
NOT_YET_RECRUITINGWürzburg, 97078, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Valkyrie Clinical Trials
RECRUITINGLos Angeles, California, 90067, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••