New drug hopes to tackle MASH cirrhosis

NCT ID NCT07325526

Recruiting now Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 6 times

Summary

This study tests a new medicine called BI 3802876 in adults with compensated cirrhosis caused by MASH (a type of fatty liver disease). The main goal is to see if the drug is safe and how the body handles it. Participants receive either the drug or a placebo as an infusion, and are followed for about six months with 12 clinic visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BI 3802876 (a drug given as an infusion into a vein)
What this could lead to: If successful, this could point toward a treatment to improve liver health in people with MASH-related cirrhosis.
What could go wrong: This is an early Phase 2 trial with only 29 participants, so results may not apply to everyone. The drug may cause side effects or fail to show benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver cirrhosis, familial metabolic dysfunction-associated steatohepatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER CIRRHOSIS

Contacts and locations

Locations

American Research Corporation at the Texas Liver Institute
RECRUITING

San Antonio, Texas, 78215, United States
Arizona Clinical Trials - Chandler
NOT_YET_RECRUITING

Chandler, Arizona, 85225, United States
Baylor Scott & White Research Institute
NOT_YET_RECRUITING

Dallas, Texas, 75246, United States
Catalina Research Institute, LLC
RECRUITING

Montclair, California, 91763, United States
Centricity Research Columbus Georgia Multispecialty
RECRUITING

Columbus, Georgia, 31904, United States
Columbia University Medical Center
NOT_YET_RECRUITING

New York, New York, 10032, United States
Covenant Metabolic Specialists, LLC - University Park
RECRUITING

University Park, Florida, 34201, United States
Epic Medical Research - Carrollton
RECRUITING

Carrollton, Texas, 75006, United States
Epic Medical Research - Fort Worth
RECRUITING

Fort Worth, Texas, 76120, United States
Houston Methodist Hospital
NOT_YET_RECRUITING

Houston, Texas, 77030, United States
Johns Hopkins Hospital
NOT_YET_RECRUITING

Baltimore, Maryland, 21287, United States
Kaiser Permanente - Los Angeles Medical Center
NOT_YET_RECRUITING

Los Angeles, California, 90027, United States
Lucas Research, Inc.
RECRUITING

Morehead City, North Carolina, 28557, United States
Mayo Clinic, Rochester
NOT_YET_RECRUITING

Rochester, Minnesota, 55905, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Nashville General Hospital
RECRUITING

Nashville, Tennessee, 37209, United States
Panax Clinical Research
RECRUITING

Miami Lakes, Florida, 33014, United States
Peak Gastroenterology Associates
RECRUITING

Colorado Springs, Colorado, 80907, United States
Pioneer Research Solutions, Inc.
RECRUITING

Houston, Texas, 77099, United States
Schiff Center Liver Diseases
NOT_YET_RECRUITING

Miami, Florida, 33136, United States
Southern California Research Center
RECRUITING

Coronado, California, 92118, United States
Texas Clinical Research Institute, LLC
NOT_YET_RECRUITING

Arlington, Texas, 76012, United States
The Liver Institute at Methodist Dallas
NOT_YET_RECRUITING

Dallas, Texas, 75203, United States
University of Alberta Hospital (University of Alberta)
NOT_YET_RECRUITING

Edmonton, Alberta, T6G 2XB, Canada
University of Iowa Hospitals and Clinics
NOT_YET_RECRUITING

Iowa City, Iowa, 52242, United States
University of Kansas Medical Center
NOT_YET_RECRUITING

Kansas City, Kansas, 66160, United States
Velocity Clinical Research, San Diego
NOT_YET_RECRUITING

La Mesa, California, 91942, United States

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