New hope for hard-to-treat cancers? drug combo enters human testing

NCT ID NCT04219254

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 25 times

Summary

This early-stage trial tests a new antibody (BI-1206) combined with an existing immunotherapy (pembrolizumab) in adults with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if the combination is safe and can help control the disease. About 197 people will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centrul de Oncologie SF Nectarie SRL

    RECRUITING

    Craiova, Romania

    Contact

  • Clinica Universidad de Navarra

    RECRUITING

    Pamplona, Spain

    Contact

  • HealthPartners Institute - Regions Cancer Care Center,

    COMPLETED

    Saint Paul, Minnesota, 55101, United States

  • Hospital Puerta de Hierro

    NOT_YET_RECRUITING

    Majadahonda, Spain

    Contact

  • Hospital Universitari Dexeus

    RECRUITING

    Barcelona, Spain

    Contact

  • Hospital Universitari Vall D´Hebron

    RECRUITING

    Barcelona, Spain

    Contact

  • Hospital Virgen de la Macarena

    RECRUITING

    Seville, Spain

    Contact

  • Institut Català d'Oncologia Hospital Duran i Reynals

    RECRUITING

    Barcelona, Spain

    Contact

  • Institutul Oncologic "Prof. Dr. Ion Chiricuta"

    RECRUITING

    Cluj-Napoca, Romania

    Contact

  • Instytut Centrum Zdrowia Matki Polki

    RECRUITING

    Lodz, Poland

    Contact

  • Israel-Georgian Medical Research Clinic Helsicore

    TERMINATED

    Tbilisi, Georgia

  • Jerarsi Clinic

    RECRUITING

    Tbilisi, Georgia

    Contact

  • Karolinska University Hospital, Solna

    RECRUITING

    Stockholm, Sweden

    Contact

  • LTD High Technology Hospital Med Center

    RECRUITING

    Batumi, Georgia

    Contact

  • Lund University Hospital

    RECRUITING

    Lund, Sweden

    Contact

  • Maria Skłodowska-Curie National Institute of Oncology

    TERMINATED

    Gliwice, Poland

  • Medical University of Silesia

    NOT_YET_RECRUITING

    Katowice, Poland

    Contact

  • Medizinische Hochschule Hannover

    NOT_YET_RECRUITING

    Hanover, Germany

    Contact

  • NEXT Oncology

    COMPLETED

    San Antonio, Texas, 78229, United States

  • Nationales Centrum für Tumorerkrankungen

    NOT_YET_RECRUITING

    Heidelberg, Germany

    Contact

  • Oklahoma University , Stephenson Cancer Center

    COMPLETED

    Oklahoma City, Oklahoma, 73104, United States

  • Sahlgrenska University Hospital

    COMPLETED

    Gothenburg, Sweden

  • Sarah Cannon Research Institute

    COMPLETED

    Denver, Colorado, 80218, United States

  • University of California Los Angeles

    NOT_YET_RECRUITING

    Los Angeles, California, 90024, United States

    Contact

  • Universität des Saarlandes

    NOT_YET_RECRUITING

    Homburg, Germany

    Contact

Conditions

Explore the condition pages connected to this study.