New hope for rare burning pain: drug trial targets genetic cause

NCT ID NCT07262268

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests whether BHV-7000 can reduce chronic pain in people with inherited erythromelalgia, a rare condition causing severe burning pain due to a genetic mutation. Only 5 adults with a specific NaV1.7 mutation will participate, comparing the drug to a placebo in a crossover design. The main goal is to see if daily pain scores improve.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Site-001

    New Haven, Connecticut, 06520, United States