New drug tested to calm severe bipolar mania

NCT ID NCT06419582

Summary

This study tested whether an investigational drug called BHV-7000 is safe and effective for quickly reducing symptoms of a manic episode in people hospitalized with Bipolar I Disorder. Over 270 adult participants received either the drug or a placebo (inactive substance) for 21 days while staying in the hospital. Researchers measured changes in manic symptoms, depression, and safety to see if BHV-7000 could help control this acute phase of the illness.

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Contacts and locations

Locations

  • Advanced Research Center, Inc.

    Anaheim, California, 92805, United States

  • Arch Clinical Trials

    St Louis, Missouri, 63141, United States

  • Atlanta Center for Medical Research

    Atlanta, Georgia, 30331, United States

  • CBH Health

    Gaithersburg, Maryland, 20877, United States

  • CIT IE

    Riverside, California, 92506, United States

  • CIT LA

    Bellflower, California, 90706, United States

  • CenExel iResearch, LLC

    Decatur, Georgia, 30030, United States

  • CenExel iResearch, LLC

    Savannah, Georgia, 31405, United States

  • Cenexel - RCA

    Hollywood, Florida, 33024, United States

  • Cenexel CNS

    Garden Grove, California, 92845, United States

  • Cenexel CNS

    Torrance, California, 90504, United States

  • Community Clinical Research, Inc.

    Austin, Texas, 78754, United States

  • Floridian Neuroscience Institute

    Miami Lakes, Florida, 33016, United States

  • Hassman Research Institute

    Marlton, New Jersey, 08053, United States

  • InSite Clinical Research, LLC

    DeSoto, Texas, 75115, United States

  • LCC Medical Research Inst

    Miami, Florida, 33126, United States

  • Midwest Clinical Research Center

    Dayton, Ohio, 45417, United States

  • NBCR

    North Canton, Ohio, 44720, United States

  • NRC Research Institute

    Orange, California, 92868, United States

  • Neuroscience Research Institute

    West Palm Beach, Florida, 33407, United States

  • Pillar Clinical Research

    Chicago, Illinois, 60641, United States

  • Pillar Clinical Research, LLC

    Bentonville, Arkansas, 72712, United States

  • Pillar Clinical Research, LLC

    Richardson, Texas, 75080, United States

  • Precise Clinical Research

    Flowood, Mississippi, 39232, United States

  • ProScience Research Group

    Culver City, California, 90230, United States

  • RBA

    Staten Island, New York, 10329, United States

  • Segal Trials - Larkin Behavioral Health Services-Inpatient & Early Phase Site

    Hollywood, Florida, 33021, United States

  • Segal Trials - Miami Lakes Medical Research-Inpatient & Early Phase Site

    Miami Lakes, Florida, 33016, United States

  • Synergy San Diego

    Lemon Grove, California, 91945, United States

  • Uptown Research Institute

    Chicago, Illinois, 60640, United States

  • WIRG

    Little Rock, Arkansas, 72211, United States

  • WRN

    Rogers, Arkansas, 72758, United States

Conditions

Explore the condition pages connected to this study.