New hope for advanced breast cancer: phase 3 trial compares novel combo to standard care
NCT ID NCT07492641
First seen Mar 26, 2026 · Last updated Apr 28, 2026 · Updated 5 times
Summary
This study tests a new drug called BGB-43395 combined with letrozole against standard CDK4/6 inhibitor drugs (abemaciclib, palbociclib, or ribociclib) plus letrozole in people with advanced or metastatic HR+/HER2- breast cancer who haven't had prior treatment for advanced disease. The goal is to see if the new combination works better at delaying cancer growth. About 1056 adults will take part, and the study is not yet recruiting.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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