First human test of experimental cancer drug halted

NCT ID NCT05381909

Summary

This early-stage study aimed to find a safe dose of a new drug called BGB-24714 for people with advanced solid tumors that have spread or cannot be removed by surgery. Researchers tested the drug by itself and combined with chemotherapy or radiation to see how well patients tolerated it and if it showed any signs of fighting the cancer. The study was terminated and involved 157 participants who had already tried standard treatments.

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Contacts and locations

Locations

  • Asan Medical Center

    SongpaGu, Seoul Teugbyeolsi, 05505, South Korea

  • Auckland City Hospital

    Auckland, 1023, New Zealand

  • Austin Health

    Heidelberg, Victoria, VIC 3084, Australia

  • Avera Cancer Institute

    Sioux Falls, South Dakota, 57105-2108, United States

  • Banner Md Anderson Cancer Center

    Gilbert, Arizona, 85234-2165, United States

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48201-2013, United States

  • Chongqing Cancer Hospital

    Chongqing, Chongqing Municipality, 400030, China

  • Florida Cancer Specialist (Scri) Sarasota

    Sarasota, Florida, 34232, United States

  • Gachon University Gil Medical Center

    NamdongGu, Incheon Gwang'yeogsi, 21565, South Korea

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601-1915, United States

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450000, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410013, China

  • Icon Cancer Centre South Brisbane

    South Brisbane, Queensland, QLD 4101, Australia

  • Intermountain Healthcare

    Salt Lake City, Utah, 84143, United States

  • Mary Crowley Cancer Research

    Dallas, Texas, 75230, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • National Cancer Center (Korea)

    IlsandongGu GoyangSi, Gyeonggi-do, 10408, South Korea

  • Next Virginia

    Fairfax, Virginia, 22031, United States

  • Northern Beaches Hospital

    Frenchs Forest, New South Wales, NSW 2086, Australia

  • Peter Maccallum Cancer Centre

    Melbourne, Victoria, VIC 3000, Australia

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, QLD 4102, Australia

  • Samsung Medical Center

    GangnamGu, Seoul Teugbyeolsi, 06351, South Korea

  • Sanford Cancer Center

    Sioux Falls, South Dakota, 57104-4663, United States

  • Scri Florida Cancer Specialist East

    West Palm Beach, Florida, 33401-3406, United States

  • Scri Florida Cancer Specialists North

    St. Petersburg, Florida, 33705-1449, United States

  • Severance Hospital Yonsei University Health System

    SeodaemunGu, Seoul Teugbyeolsi, 03722, South Korea

  • Shandong Cancer Hospital

    Jinan, Shandong, 250117, China

  • Shandong Provincial Hospital

    Jinan, Shandong, 250021, China

  • Sunshine Hospital

    St Albans, Victoria, VIC 3021, Australia

  • Tennessee Oncology, Pllc Nashville

    Nashville, Tennessee, 37203, United States

  • The University of Texas Md Anderson Cancer Center (Department Gi Medical Oncology)

    Houston, Texas, 77030-4000, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-7208, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Upmc Hillman Cancer Center(Univ of Pittsburgh)

    Pittsburgh, Pennsylvania, 15232-1309, United States

Conditions

Explore the condition pages connected to this study.