New hope for Tough-to-Treat blood cancers: Head-to-Head drug trial launches

NCT ID NCT06973187

Recruiting now Disease control Sponsor: BeOne Medicines Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 30 times

Summary

This study tests a new drug, BGB-16673, against another drug, pirtobrutinib, in people whose chronic lymphocytic leukemia or small lymphocytic lymphoma has returned or stopped responding to prior treatment. About 500 participants will receive one of the two drugs to see which works better at controlling the cancer and with fewer side effects. The goal is to improve disease control, not to cure the condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

Aiiku Hospital
RECRUITING

Sapporo, Hokkaido, 064-0804, Japan
Albert Schweitzer Ziekenhuis
RECRUITING

Dordrecht, 3318 AT, Netherlands
Atrium Health Levine Cancer Institute (Lci)
RECRUITING

Charlotte, North Carolina, 28204-2990, United States
Austin Health
RECRUITING

Heidelberg, Victoria, VIC 3084, Australia
Auxilio Mutuo Cancer Center
RECRUITING

San Juan, 00917, Puerto Rico
Az Groeninge Campus Loofstraat
RECRUITING

Kortrijk, 8500, Belgium
Az Sint Maarten
RECRUITING

Mechelen, 2800, Belgium
Azienda Ospedaliera Di Padova
RECRUITING

Padova, 35128, Italy
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
RECRUITING

Milan, 20162, Italy
Blue Ridge Cancer Care (Oncology and Hematology Associates of Southwest Virginia)
RECRUITING

Roanoke, Virginia, 24014, United States
Bnai Zion Medical Center
RECRUITING

Haifa, 31048, Israel
Cabrini Hospital Malvern
RECRUITING

Malvern East, Victoria, VIC 3144, Australia
Cancer Institute Hospital of Jfcr
RECRUITING

Kotoku, Tokyo, 135-8550, Japan
Cancer Specialists of North Florida
RECRUITING

Jacksonville, Florida, 001625, United States
Cancer and Blood Specialty Clinic
RECRUITING

Los Alamitos, California, 90720-3302, United States
Canisius Wilhelmina Ziekenhuis
RECRUITING

Nijmegen, 6532 SZ, Netherlands
Catharina Hospital
RECRUITING

EJ Eindhoven, 5623, Netherlands
Centre Henri Becquerel
RECRUITING

Rouen, 76038, France
Centre Hospitalier Universitaire Nantes Hotel Dieu
RECRUITING

Nantes, 44000, France
Centre de Lutte Contre Le Cancer Institut Bergonie
RECRUITING

Bordeaux, 33000, France
Centro de Pesquisa Clinica Dom Bosco Ltda
RECRUITING

Araçatuba, 16015-150, Brazil
Chc Montlegia
RECRUITING

Liège, 4000, Belgium
Christiana Care
RECRUITING

Newark, Delaware, 19713-2055, United States
Chu Nancy Hopital Brabois
RECRUITING

VandoeuvrelesNancy, 54511, France
Chu Tours Hopital Bretonneau
RECRUITING

Tours, 37000, France
Chu Ucl Namur
RECRUITING

Yvoir, 5530, Belgium
Chu de Liege
RECRUITING

Liège, 4000, Belgium
Coltea Clinical Hospital
RECRUITING

Bucharest, 30171, Romania
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Concord Repatriation General Hospital
RECRUITING

Concord, New South Wales, NSW 2139, Australia
Copernicus Podmiot Leczniczy Sp Z Oo Wojewodzkie Centrum Onkologii
RECRUITING

Gdansk, 80-219, Poland
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215-5418, United States
Dayton Physician Network
RECRUITING

Dayton, Ohio, 45415, United States
Dokkyo Medical University Saitama Medical Center
RECRUITING

Koshigaya, Saitama, 503-8502, Japan
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27705-3976, United States
Ensino E Terapia de Inovacao Clinica Amo Etica
RECRUITING

Salvador, 41950-640, Brazil
Flinders Medical Centre
RECRUITING

Bedford PK, South Australia, SA 5042, Australia
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111-2434, United States
Fred Hutchinson Cancer Research Center
RECRUITING

Seattle, Washington, 98109-4433, United States
Fukushima Medical University Hospital
RECRUITING

Fukushima, Fukushima, 960-1295, Japan
Gemeinschaftspraxis Fuer Haematologie Und Onkologie Westerstede
RECRUITING

Westerstede, 26655, Germany
Gemeinschaftspraxis Fur Hamatologie Und Onkologie Dortmund
RECRUITING

Dortmund, 44309, Germany
Groene Hart Hospital
RECRUITING

Gouda, 2803, Netherlands
Gunderson Health System
RECRUITING

La Crosse, Wisconsin, 54601-5467, United States
Gyeongsang National University Hospital
RECRUITING

Jinju, Gyeongsangnam-do, 52727, South Korea
Hadassah University Hospital Ein Kerem
RECRUITING

Jerusalem, 91120, Israel
Hcfmusp Hospital Das Clinicas Da Faculdade de Medicina Da Universidade de Sao Paulo
RECRUITING

São Paulo, 05403-010, Brazil
Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital
RECRUITING

Hiroshima, Hiroshima, 730-8619, Japan
Hopital Estaing
RECRUITING

Clermontferrand, 63100, France
Hopital Saint Louis
RECRUITING

Paris, 75010, France
Hospital Nove de Julho Dasa
RECRUITING

São Paulo, 01409-001, Brazil
Hospital Universitari Son Espases
RECRUITING

Palma de Mallorca, 07120, Spain
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hospital Universitario Puerta de Hierro Majadahonda
RECRUITING

Majadahonda, 28222, Spain
Hospital Universitario Virgen Del Rocio
RECRUITING

Seville, 41013, Spain
Hospital Universitario de Burgos
RECRUITING

Burgos, 09006, Spain
Hospital Universitario de Gran Canaria Dr Negrin
RECRUITING

Las Palmas de Gran Canaria, 35010, Spain
Hospital de Clinicas de Goiania Ufg
RECRUITING

Goiânia, 74605-020, Brazil
Hull Royal Infirmary
RECRUITING

Hull, HU3 2JZ, United Kingdom
Ico Badalona
RECRUITING

Badalona, 08916, Spain
Ictr Instituto Do Cancer E Transplante de Curitiba
RECRUITING

Curitiba, 80510-130, Brazil
Inca Instituto Nacional de Cancer
RECRUITING

Rio de Janeiro, 20231-050, Brazil
Inselspital Bern (Inselspital, Universitatsspital Bern)
RECRUITING

Bern, 3010, Switzerland
Institut Jules Bordet
RECRUITING

Anderlecht, 1070, Belgium
Institutul Oncologic Prof Dr Ion Chiricuta Cluj Napoca
RECRUITING

ClujNapoca, 400015, Romania
Institutul Regional de Oncologie Iasi
RECRUITING

Iași, 700483, Romania
Iuc Toulouse Oncopole
RECRUITING

Toulouse, 31100, France
Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital
RECRUITING

Nakamuraku, Aichi-ken, 453-8511, Japan
Japanese Red Cross Kyoto Daini Hospital
RECRUITING

Kyotoshi, Kyoto, 602-8026, Japan
John Theurer Cancer Center Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601-2191, United States
Kaiser Permanente Southern California
RECRUITING

Irvine, California, 92618-3734, United States
Karmanos Cancer Institute
RECRUITING

Detroit, Michigan, 48201-2013, United States
Karolinska Universitetssjukhuset Solna
RECRUITING

Stockholm, 171 76, Sweden
Kent and Canterbury Hospital
RECRUITING

Canterbury, CT1 3NG, United Kingdom
Kindai University Hospital
RECRUITING

Sakai, Osaka, 590-0197, Japan
Kochi Medical School Hospital
RECRUITING

Nankoku, Kochi, 783-8505, Japan
Kumamoto University Hospital
RECRUITING

Kumamoto, 860-8556, Japan
Linear Clinical Research
RECRUITING

Nedlands, Western Australia, WA 6009, Australia
Luebecker Onkologische Schwerpunktpraxis Dres Med Kisroweber
RECRUITING

Lübeck, 23562, Germany
Mary Bird Perkins Cancer Center
RECRUITING

Baton Rouge, Louisiana, 70809-3738, United States
Matsuyama Red Cross Hospital
RECRUITING

Matsuyama, Ehime, 790 8524, Japan
Mayo Clinic Jacksonville
RECRUITING

Jacksonville, Florida, 32224-1865, United States
Mayo Clinic Phoenix
RECRUITING

Phoenix, Arizona, 85054-4502, United States
Mayo Clinic Rochester
RECRUITING

Rochester, Minnesota, 55905-0001, United States
Md Anderson Cancer Center
RECRUITING

Houston, Texas, 77030-3907, United States
Medizinische Universitatsklinik Innsbruck
RECRUITING

Innsbruck, 6020, Austria
Meir Medical Center
RECRUITING

KfarSava, 4428164, Israel
Memorial Sloan Kettering Cancer Center Mskcc
RECRUITING

New York, New York, 10065-6800, United States
Mount Sinai Comprehensive Cancer Center
RECRUITING

Miami, Florida, 33140-2840, United States
Narodowy Instytut Onkologii Im Marii Sklodowskiej Curie Hematology Unit
RECRUITING

Warsaw, 02-781, Poland
National Hospital Organization (Nho) Disaster Medical Center
RECRUITING

Tachikawashi, Tokyo, 190-0014, Japan
Norfolk and Norwich University Hospitals Nhs Foundation Trust
RECRUITING

Norwich, NR4 7UY, United Kingdom
North Shore Hospital
RECRUITING

Auckland, 0622, New Zealand
Northwest Medical Specialties
RECRUITING

Tacoma, Washington, 98405, United States
Ochsner Clinic Foundation
RECRUITING

New Orleans, Louisiana, 70121-2429, United States
Oita Prefectural Hospital
RECRUITING

Ōita, 870-8511, Japan
Okayama University Hospital
RECRUITING

Okayama, Okayama-ken, 700-8558, Japan
Ordensklinikum Linz Gmbh Elisabethinen
RECRUITING

Linz, 4020, Austria
Osaka Metropolitan University Hospital
RECRUITING

Osaka, 545-8586, Japan
Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy
Our Lady of the Lake Hospital
RECRUITING

Baton Rouge, Louisiana, 70808-4365, United States
Peninsula Private Hospital
RECRUITING

Frankston, Victoria, VIC 3199, Australia
Peter Maccallum Cancer Centre
RECRUITING

Melbourne, Victoria, VIC 3000, Australia
Policlinico Sorsola Malpighi, Aou Di Bologna
RECRUITING

Bologna, 40138, Italy
Pusan National University Hospital
RECRUITING

Seogu, Busan Gwang'yeogsi, 49241, South Korea
Rabin Medical Center
RECRUITING

Petah Tikva, 49100, Israel
Sahlgrenska Universitetssjukhuset
RECRUITING

Gothenburg, 413 46, Sweden
Salisbury Foundation Trust
RECRUITING

Salisbury, SP2 8BJ, United Kingdom
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, Seoul Teugbyeolsi, 03080, South Korea
Severance Hospital Yonsei University Health System
RECRUITING

SeodaemunGu, Seoul Teugbyeolsi, 03722, South Korea
Shaare Zedek Medical Center
RECRUITING

Jerusalem, 9103102, Israel
Sheba Medical Center
RECRUITING

Ramat Gan, 5262100, Israel
Singapore General Hospital
RECRUITING

Singapore, 168582, Singapore
Sourasky Tel Aviv Medical Center
RECRUITING

Tel Aviv, 6423906, Israel
Spire Leeds Healthcare Spire Leeds Hospital
RECRUITING

Roundhay, LS8 1NT, United Kingdom
St Vincents Hospital Melbourne
RECRUITING

Fitzroy, Victoria, VIC 3065, Australia
Stanford Cancer Institute
RECRUITING

Palo Alto, California, 94304-2205, United States
Summit Cancer Centers
RECRUITING

Spokane, Washington, 99208-1129, United States
Sunshine Coast Hospital and Health Service
RECRUITING

Birtinya, Queensland, QLD 4575, Australia
Swietokrzyskie Centrum Onkologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej W Kielcach
RECRUITING

Kielce, 25-734, Poland
Szpital Kliniczny Mswia Z Warmisko Mazurskim Centrum Onkologii
RECRUITING

Olsztyn, 10-228, Poland
Tan Tock Seng Hospital Haematology
RECRUITING

Singapore, 308433, Singapore
Tauranga Hospital
RECRUITING

Tauranga, 3112, New Zealand
Tennessee Oncology, Pllc Nashville
RECRUITING

Nashville, Tennessee, 37203, United States
The Alfred Hospital
RECRUITING

Melbourne, Victoria, VIC 3004, Australia
The Catholic University of Korea, Seoul St Marys Hospital
RECRUITING

SeochoGu, Seoul Teugbyeolsi, 06591, South Korea
The University of Kansas Cancer Center
RECRUITING

Westwood, Kansas, 66205-2003, United States
Titan Health Partners Llc Dba Astera Cancer Care
RECRUITING

East Brunswick, New Jersey, 08816-4096, United States
Tokyo Metropolitan Komagome Hospital
RECRUITING

Bunkyoku, Tokyo, 113-8677, Japan
UCLA Department of Medicine Hematologyoncology
RECRUITING

Los Angeles, California, 90095-3075, United States
UZ GENT
RECRUITING

Ghent, 9000, Belgium
Uk St Poelten
RECRUITING

Sankt Pölten, 3100, Austria
Universitaetsklinikum Ulm
RECRUITING

Ulm, 89081, Germany
Universitair Medisch Centrum Utrecht
RECRUITING

Utrecht, 3584 CX, Netherlands
Universitatsspital Zurich
RECRUITING

Zurich, 8091, Switzerland
University Hospitals Sussex Nhs Foundation Trust
RECRUITING

Brighton, BN2 5BE, United Kingdom
University of California San Diego (Ucsd) Moores Cancer Center
RECRUITING

La Jolla, California, 92093-1503, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637-1443, United States
University of Medical Center Groningen (Umcg)
RECRUITING

Groningen, 9713 GZ, Netherlands
University of North Carolina At Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514-4220, United States
University of Rochester
RECRUITING

Rochester, New York, 14642-0001, United States
Uniwersytecki Szpital Kliniczny Im Jana Mikulicza Radeckiego We Wroclawiu
RECRUITING

Wroclaw, 50-367, Poland
Uniwersytecki Szpital Kliniczny Nr 1 W Lublinie Uniwersytet Medyczny W Lublinie
RECRUITING

Lublin, 20-400, Poland
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110-1010, United States
Wellington Regional Hospital (Ccdhb)
RECRUITING

Wellington, 6021, New Zealand
Wielospecjalistyczne Centrum Onkologii I Traumatologii Im M Kopernika W Lodzi
RECRUITING

Lodz, 93-513, Poland
Wojewodzki Szpital Zespolony Im L Rydygiera W Toruniu
RECRUITING

Torun, 87-100, Poland
Yamagata University Hospital
RECRUITING

Yamagata, Yamagata, 990-9585, Japan

Conditions

Explore the condition pages connected to this study.

CHRONIC LYMPHOCYTIC LEUKEMIA SMALL LYMPHOCYTIC LYMPHOMA