New Triple-Action antibody takes on Hard-to-Treat cancers
NCT ID NCT06598800
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study tests a new drug called BG-T187, a special antibody that targets two proteins (EGFR and MET) on cancer cells. It is given alone or with other drugs to people with advanced solid tumors that have spread or cannot be removed. The main goals are to check safety, find the right dose, and see if the drug can shrink tumors. About 153 participants will take part in this first-in-human trial.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BG-T187 (a trispecific antibody targeting EGFR and MET proteins)
What this could lead to
If successful, this could lead to a new treatment option for people with advanced solid tumors that have not responded to other therapies.
What could go wrong
This is an early phase 1 trial with only 153 participants, so the drug may not be safe or effective. Side effects could be serious, and the drug may not shrink tumors.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Locations
-
Asan Medical Center
RECRUITINGSongpaGu, Seoul Teugbyeolsi, 05505, South Korea
-
Blacktown Cancer and Haematology Centre
RECRUITINGBlacktown, New South Wales, NSW 2148, Australia
-
Cabrini Hospital Malvern
RECRUITINGMalvern, Victoria, VIC 3144, Australia
-
Cancer Hospital Chinese Academy of Medical Sciences
RECRUITINGBeijing, Beijing Municipality, 100021, China
-
Chongqing University Cancer Hospital
RECRUITINGChongqing, Chongqing Municipality, 400030, China
-
Fujian Cancer Hospital
RECRUITINGFuzhou, Fujian, 350014, China
-
Guangxi Medical University Cancer Hospital
RECRUITINGNanning, Guangxi, 530021, China
-
Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601-1915, United States
-
Harbin Medical University Cancer Hospital
RECRUITINGHarbin, Heilongjiang, 150000, China
-
Hubei Cancer Hospital
RECRUITINGWuhan, Hubei, 430079, China
-
Linear Clinical Research
RECRUITINGNedlands, Western Australia, WA 6009, Australia
-
Linyi Peoples Hospital
RECRUITINGLinyi, Shandong, 276000, China
-
Macquarie University
RECRUITINGNorth Ryde, New South Wales, NSW 2109, Australia
-
Next Virginia
RECRUITINGFairfax, Virginia, 22031, United States
-
Samsung Medical Center
RECRUITINGGangnamGu, Seoul Teugbyeolsi, 06351, South Korea
-
Seoul National University Bundang Hospital
RECRUITINGSeongnam-si, Gyeonggi-do, 13620, South Korea
-
Seoul National University Hospital
RECRUITINGSeoul, Seoul Teugbyeolsi, 03080, South Korea
-
Severance Hospital Yonsei University Health System
RECRUITINGSeodaemunGu, Seoul Teugbyeolsi, 03722, South Korea
-
The Catholic University of Korea, Seoul St Marys Hospital
RECRUITINGSeochoGu, Seoul Teugbyeolsi, 06591, South Korea
-
The Catholic University of Korea, St Vincents Hospital
RECRUITINGPaldalGu SuwonSi, Gyeonggi-do, 16247, South Korea
-
The First Affiliated Hospital, Zhejiang University School of Medicinezhijiang Branch
RECRUITINGHangzhou, Zhejiang, 310024, China
-
The Sixth Affiliated Hospital, Sun Yat Sen University
RECRUITINGGuangzhou, Guangdong, 510655, China
-
The University of Texas Md Anderson Cancer Center
RECRUITINGHouston, Texas, 77030-4009, United States
-
Tianjin Medical University Cancer Institute and Hospital
RECRUITINGTianjin, Tianjin Municipality, 300060, China
-
Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430030, China
-
Washington University, St Louis, Division of Oncology
RECRUITINGMadison, Wisconsin, 53708-8056, United States