New pill shows promise in early cancer trial

NCT ID NCT07222267

Recruiting now Disease control Sponsor: BeOne Medicines Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 5 times

Summary

This early-phase study is testing a new oral drug called BG-75202, alone or with other medications, in people with advanced breast cancer or other solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it shows any signs of shrinking tumors. About 86 participants will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BG-75202 (a KAT6A/B inhibitor taken as a pill)
What this could lead to: If successful, this could point toward a new treatment option for people with advanced breast cancer or other solid tumors that have stopped responding to standard therapies.
What could go wrong: This is a very early (Phase 1) trial with only 86 participants, so it is primarily testing safety and dosing. It is too soon to know if the drug will effectively shrink tumors or improve survival.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMOR BREAST CANCER

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Auckland City Hospital
NOT_YET_RECRUITING

Auckland, Grafton, 1023, New Zealand
Austin Health
RECRUITING

Heidelberg, Victoria, VIC 3084, Australia
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100142, China
Blacktown Cancer and Haematology Centre
RECRUITING

Blacktown, New South Wales, NSW 2148, Australia
Cancer Hospital Chinese Academy of Medical Sciences
RECRUITING

Beijing, Beijing Municipality, 100021, China
Cancer Research South Australia
RECRUITING

Adelaide, South Australia, SA 5000, Australia
Chongqing University Cancer Hospital
RECRUITING

Chongqing, Chongqing Municipality, 400030, China
Chris Obrien Lifehouse
RECRUITING

Camperdown, New South Wales, NSW 2050, Australia
Fondazione Policlinico Universitario Agostino Gemelli
RECRUITING

Roma, 00168, Italy
Fred Hutchinson Cancer Research Center
RECRUITING

Seattle, Washington, 98109-4433, United States
Fudan University Shanghai Cancer Centerpudong
RECRUITING

Shanghai, Shanghai Municipality, 201321, China
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150000, China
Hospital Clinico San Carlos
RECRUITING

Madrid, 28240, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Vall Dhebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Virgen de La Victoria
RECRUITING

Málaga, 29010, Spain
Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy
Istituto Europeo Di Oncologia
RECRUITING

Milan, 20141, Italy
Istituto Nazionale Tumori Fondazione G Pascale
RECRUITING

Naples, 80131, Italy
Jiangsu Province Hospital Longjiang Branch
RECRUITING

Nanjing, Jiangsu, 210036, China
Next Oncology Austin
RECRUITING

Austin, Texas, 78758, United States
Next Oncology Barcelona
RECRUITING

Barcelona, 8023, Spain
Peter Maccallum Cancer Centre
RECRUITING

Melbourne, Victoria, VIC 3000, Australia
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310016, China
Sun Yat Sen University Cancer Center Huangpu Branch
RECRUITING

Guangzhou, Guangdong, 510555, China
The First Affiliated Hospital of Xiamen University
RECRUITING

Xiamen, Fujian, 361003, China
The University of Texas Md Anderson Cancer Center
RECRUITING

Houston, Texas, 77030-4009, United States
Tianjin Medical University Cancer Institute and Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300060, China
University of Alabama At Birmingham Hospital
RECRUITING

Birmingham, Alabama, 35294-0004, United States
Washington University in St Louis
RECRUITING

St Louis, Missouri, 63110-1010, United States
Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06510, United States

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