Could a cancer drug replace liver transplants for HHT patients?

NCT ID NCT00843440

First seen Jan 04, 2026 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tested a drug called bevacizumab in 25 adults with hereditary hemorrhagic telangiectasia (HHT) who had severe liver blood vessel problems and high cardiac output. The goal was to see if the drug could improve heart function and avoid the need for a liver transplant, which requires lifelong immune-suppressing medication. The approach uses the drug's ability to block abnormal blood vessel growth.

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Contacts and locations

Locations

  • Hospices Civils de Lyon

    Lyon, France

Conditions

Explore the condition pages connected to this study.