Could a cancer drug tame dangerous brain vessels?

This study tests whether the drug bevacizumab, given through a vein, can improve symptoms like headaches, seizures, and thinking problems in people with brain arteriovenous malformations (AVMs) that are too large or risky for surgery or radiation. About 54 adults with moderate to severe symptoms will receive the drug to see if it reduces their disability. The goal is symptom control, not a cure, and participants may still need other treatments.