New scan could spot parathyroid tumors that old tests miss

NCT ID NCT05891769

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a newer PET scan using 18F fluorocholine can find parathyroid adenomas that standard SPECT/CT scans miss. About 100 adults with high calcium and negative or unclear standard scans will receive the new scan. The goal is to see if the new method detects more adenomas, which could help guide surgery and improve outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
18F fluorocholine
What this could lead to
If successful, this could offer a more accurate way to spot parathyroid adenomas, helping more patients get the right surgery without unnecessary neck exploration.
What could go wrong
This is a small, early-phase study (Phase 2/3) with only 100 participants. The new scan may not find more adenomas than the standard test, and false positives could lead to unnecessary procedures.

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Conditions

The condition(s) this trial relates to.

parathyroid gland adenoma Parathyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Stanford Hospital and Clinics

    RECRUITING

    Stanford, California, 94305, United States

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