New ultrasound technique could spare infants from invasive brain monitoring

NCT ID NCT06693752

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special ultrasound with a contrast dye can safely and effectively measure brain health in infants with hydrocephalus, a condition where fluid builds up in the brain. About 20 infants under 1.5 years old will receive an injection of the contrast agent through an IV, followed by an ultrasound. The goal is to see if this method can replace or reduce the need for invasive pressure monitors and shunts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sulfur hexafluoride lipid-type A microspheres (contrast agent)

What this could lead to

If successful, this could lead to a safer, non-invasive way to monitor brain pressure and blood flow in infants with hydrocephalus, reducing reliance on invasive shunts.

What could go wrong

This is a small pilot study with only 20 infants, so results may not apply to all cases. The contrast agent also carries a small risk of allergic reactions or side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYDROCEPHALUS IN INFANTS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hydrocephalus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact