Can a natural body compound heal fatty liver disease?
NCT ID NCT07276204
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether betaine, a natural substance found in the body, can reduce liver injury in people with MASH (a serious fatty liver disease). Seventy participants will take either betaine or placebo pills for 24 weeks, with follow-up for another 24 weeks. The main goal is to see if betaine lowers a blood-based risk score for advanced liver disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Betaine
- What this could lead to
- If it works, betaine could offer a simple, natural supplement to reduce liver injury in people with MASH.
- What could go wrong
- This is an early Phase 2 trial with only 70 people. Betaine may not improve liver health more than placebo, and results may not apply to everyone with MASH.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MASH - METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a once-daily pill help children with fatty liver disease?
- Could a common sugar fuel liver damage?
- Can eating only during an 8-10 hour window help liver cancer patients?
- Could a quick liver scan replace needle biopsies for MASH in diabetics?
- New pill could stop liver scarring in MASH patients
- New registry tracks rezdiffra safety for moms and babies