Can a natural body compound heal fatty liver disease?
NCT ID NCT07276204
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether betaine, a natural substance found in the body, can reduce liver injury in people with MASH (a serious fatty liver disease). Seventy participants will take either betaine or placebo pills for 24 weeks, with follow-up for another 24 weeks. The main goal is to see if betaine lowers a blood-based risk score for advanced liver disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Betaine
What this could lead to
If it works, betaine could offer a simple, natural supplement to reduce liver injury in people with MASH.
What could go wrong
This is an early Phase 2 trial with only 70 people. Betaine may not improve liver health more than placebo, and results may not apply to everyone with MASH.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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