New drug cocktail shows promise for rare sarcoma

NCT ID NCT07548177

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial is testing whether a combination of two drugs—benmelstobart (an immunotherapy) and anlotinib (a targeted therapy)—can shrink tumors in people with advanced or inoperable alveolar soft part sarcoma, a rare cancer. The study will enroll 33 participants aged 14 and older. The main goal is to see how many patients have a significant reduction in tumor size.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

benmelstobart injection and anlotinib hydrochloride capsules

What this could lead to

If successful, this combination could offer a new treatment option for people with advanced alveolar soft part sarcoma, potentially shrinking tumors and controlling disease progression.

What could go wrong

This is a small, early-phase trial with only 33 participants and no comparison group, so results may not apply broadly. The drugs can cause side effects like fatigue, high blood pressure, or immune-related reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alveolar soft part sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Harbin Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150081, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Cancer Hospital

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shandong First Medical University Affiliated Tumor Hospital

    NOT_YET_RECRUITING

    Jinan, Shandong, 250117, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai General Hospital

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200080, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen University Cancer Center

    NOT_YET_RECRUITING

    Guangdong, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Army Medical University of the People's Liberation Army of China

    NOT_YET_RECRUITING

    Chongqing, Chongqing Municipality, 400038, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital, Zhejiang University School of Medicine.

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The first hospital of Jilin University

    NOT_YET_RECRUITING

    Changchun, Jilin, 130021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University Cancer Institute & Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital of Sichuan University

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xiangya Hospital of Central South University

    NOT_YET_RECRUITING

    Changsha, Hunan, 410008, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xinjiang Medical University Affiliated Cancer Hospital

    NOT_YET_RECRUITING

    Ürümqi, Xinjiang, 830000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhejiang Cancer Hospital

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••