New drug combo aims to control advanced kidney cancer

NCT ID NCT05468697

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new drug combination (belzutifan plus palbociclib) against belzutifan alone in people with advanced clear-cell kidney cancer that has worsened after at least two prior treatments. The main goals are to check safety and find the best dose of palbociclib when used with belzutifan. About 60 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

clear cell renal carcinoma kidney cancer renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center-Cancer Clinical Trials Office ( Site 1001)

    Boston, Massachusetts, 02215, United States

  • Emek Medical Center-oncology ( Site 3003)

    Afula, 1834111, Israel

  • Frankston Hospital-Oncology and Haematology ( Site 2005)

    Frankston, Victoria, 3199, Australia

  • Georgetown University Medical Center ( Site 1002)

    Washington D.C., District of Columbia, 20007, United States

  • Huntsman Cancer Institute-HCI Clinical Trials Office ( Site 1004)

    Salt Lake City, Utah, 84112, United States

  • Macquarie University-MQ Health Clinical Trials Unit ( Site 2001)

    Macquarie University, New South Wales, 2109, Australia

  • One Clinical Research ( Site 2008)

    Nedlands, Western Australia, 6009, Australia

  • Rabin Medical Center-Oncology ( Site 3004)

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus-Oncology ( Site 3000)

    Haifa, 3109601, Israel

  • Shaare Zedek Medical Center-Oncology ( Site 3002)

    Jerusalem, 9103102, Israel

  • Sourasky Medical Center ( Site 3005)

    Tel Aviv, 6423906, Israel

  • University of Chicago Medical Center ( Site 1007)

    Chicago, Illinois, 60637, United States

  • Westmead Hospital ( Site 2006)

    Westmead, New South Wales, 2145, Australia