New drug trial aims to tame dangerous transplant complication

NCT ID NCT05996627

Summary

This study is testing whether the drug belumosudil can help control chronic graft-versus-host disease (cGVHD), a serious complication where the donor's immune cells attack the patient's body after a stem cell transplant. The trial will enroll 82 adult patients who have early signs of cGVHD but don't yet need strong immune-suppressing drugs. Participants will randomly receive either belumosudil or a placebo pill daily for about a year to see if the drug can delay or prevent the need for additional treatments.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

Conditions

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