Can talk therapy break the cycle of depressive rumination?

NCT ID NCT06322420

Ongoing Symptom relief Sponsor: University of Iceland Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether Behavioral Activation (BA) therapy can change the habit of repetitive negative thinking (rumination) in people with major depression. Up to 120 adults will receive 12 sessions of BA over 11 weeks. Researchers will measure symptom changes and explore who responds best to treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Behavioral Activation therapy
What this could lead to: If successful, this could show how Behavioral Activation helps reduce depressive rumination and identify who benefits most.
What could go wrong: This is a small, single-arm study without a placebo group, so results may not prove the therapy works better than no treatment or other approaches.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

University of Iceland

Reykjavik, Iceland, 102, Iceland

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