Genetic roadmap guides new hope for tough leukemia

NCT ID NCT03013998

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study screens people with acute myeloid leukemia (AML) for specific genetic markers to assign them to a treatment sub-study with a targeted drug or combination. It aims to improve response rates by personalizing therapy based on each person's cancer profile. The trial enrolls adults aged 60 and older (and some younger adults with certain genetic types) who have not been treated before or whose cancer has returned. The goal is to advance new targeted therapies for approval while managing the disease long-term.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30308, United States

    Contact

  • Huntsman Cancer Institute, University of Utah

    COMPLETED

    Salt Lake City, Utah, 84112, United States

  • Mayo Clinic Arizona

    COMPLETED

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Florida

    COMPLETED

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Minnesota

    COMPLETED

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact

  • UCLA Ronald Reagan Medical Center

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

  • UNC Hospitals, University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact

  • UPMC Hillman Cancer Center

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact

  • University of Cincinnati Medical Center

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact

  • University of Colorado

    COMPLETED

    Denver, Colorado, 80203, United States

  • University of Florida Health Shands Cancer Hospital

    COMPLETED

    Gainesville, Florida, 32608, United States

  • University of Kansas Clinical Research Center

    RECRUITING

    Fairway, Kansas, 66205, United States

    Contact

  • University of Maryland Medical Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact

  • University of Texas Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact