Genetic roadmap guides new hope for tough leukemia

NCT ID NCT03013998

Recruiting now Disease control Sponsor: Beat AML, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study screens people with acute myeloid leukemia (AML) for specific genetic markers to assign them to a treatment sub-study with a targeted drug or combination. It aims to improve response rates by personalizing therapy based on each person's cancer profile. The trial enrolls adults aged 60 and older (and some younger adults with certain genetic types) who have not been treated before or whose cancer has returned. The goal is to advance new targeted therapies for approval while managing the disease long-term.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREVIOUSLY UNTREATED RELAPSED REFRACTORY ACUTE MYELOID LEUKEMIA

Contacts and locations

Locations

Emory University
RECRUITING

Atlanta, Georgia, 30308, United States
Huntsman Cancer Institute, University of Utah
COMPLETED

Salt Lake City, Utah, 84112, United States
Mayo Clinic Arizona
COMPLETED

Phoenix, Arizona, 85054, United States
Mayo Clinic Florida
COMPLETED

Jacksonville, Florida, 32224, United States
Mayo Clinic Minnesota
COMPLETED

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
Oregon Health & Science University
RECRUITING

Portland, Oregon, 97239, United States
UCLA Ronald Reagan Medical Center
RECRUITING

Los Angeles, California, 90095, United States
UNC Hospitals, University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514, United States
UPMC Hillman Cancer Center
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
University of California, San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Colorado
COMPLETED

Denver, Colorado, 80203, United States
University of Florida Health Shands Cancer Hospital
COMPLETED

Gainesville, Florida, 32608, United States
University of Kansas Clinical Research Center
RECRUITING

Fairway, Kansas, 66205, United States
University of Maryland Medical Center
RECRUITING

Baltimore, Maryland, 21201, United States
University of Texas Southwestern
RECRUITING

Dallas, Texas, 75390, United States

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