New cocktail therapy aims to beat back stubborn leukemia

NCT ID NCT07651475

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a combination of six drugs, called the Beach regimen, in 32 adults with relapsed or refractory acute myeloid leukemia (AML). The goal is to see if this mix can bring about remission and improve survival. Participants receive the drugs in a specific schedule, and researchers track how many achieve complete remission or other positive responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
combination of BCL-2 inhibitor, Zemestosita, Azacitidine, Cytarabine, Chidamide, and G-CSF
What this could lead to
If successful, this could offer a new treatment option for patients with hard-to-treat acute myeloid leukemia, potentially leading to remission.
What could go wrong
This is a small, early-phase trial with only 32 participants, so results may not apply broadly. The drug combination may cause side effects or fail to improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chinese PLA General Hospital

    Beijing, Beijing Municipality, 100853, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.