New cocktail therapy aims to beat back stubborn leukemia

NCT ID NCT07651475

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a combination of six drugs, called the Beach regimen, in 32 adults with relapsed or refractory acute myeloid leukemia (AML). The goal is to see if this mix can bring about remission and improve survival. Participants receive the drugs in a specific schedule, and researchers track how many achieve complete remission or other positive responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

combination of BCL-2 inhibitor, Zemestosita, Azacitidine, Cytarabine, Chidamide, and G-CSF

What this could lead to

If successful, this could offer a new treatment option for patients with hard-to-treat acute myeloid leukemia, potentially leading to remission.

What could go wrong

This is a small, early-phase trial with only 32 participants, so results may not apply broadly. The drug combination may cause side effects or fail to improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chinese PLA General Hospital

    Beijing, Beijing Municipality, 100853, China