New drug combo aims to control High-Risk bladder cancer without prior treatment

NCT ID NCT05943106

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This study tests a combination of two drugs—BCG (a standard immunotherapy for bladder cancer) and durvalumab (an immune-boosting drug)—in adults with high-risk non-muscle-invasive bladder cancer who have not received BCG before. The goal is to see if the combination is safe and effective at controlling the cancer. About 100 participants across the U.S. will receive the treatment as an induction course followed by maintenance doses.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Phoenix, Arizona, 85054, United States

  • Research Site

    Little Rock, Arkansas, 72211, United States

  • Research Site

    San Diego, California, 92123, United States

  • Research Site

    Lakewood, Colorado, 80228, United States

  • Research Site

    Hialeah, Florida, 33016, United States

  • Research Site

    Jacksonville, Florida, 32209, United States

  • Research Site

    Greenwood, Indiana, 46143, United States

  • Research Site

    Wichita, Kansas, 67226, United States

  • Research Site

    Baltimore, Maryland, 21203, United States

  • Research Site

    Hanover, Maryland, 21076, United States

  • Research Site

    Royal Oak, Michigan, 48073, United States

  • Research Site

    Troy, Michigan, 48084, United States

  • Research Site

    Syracuse, New York, 13210, United States

  • Research Site

    Cincinnati, Ohio, 45212, United States

  • Research Site

    Bala-Cynwyd, Pennsylvania, 19004-1017, United States

  • Research Site

    Myrtle Beach, South Carolina, 29572, United States

  • Research Site

    Nashville, Tennessee, 37209, United States

  • Research Site

    Austin, Texas, 78759, United States

  • Research Site

    Spokane, Washington, 99202, United States

Conditions

Explore the condition pages connected to this study.