New targeted drug enters human testing for hard-to-treat lung cancer
NCT ID NCT06343402
First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 25 times
Summary
This early-stage study tests a new drug called BBO-8520 in about 350 adults with advanced non-small cell lung cancer that has a specific genetic change (KRAS G12C). The main goals are to check safety and find the right dose, while also seeing if the drug shrinks tumors. Participants will receive the drug alone or combined with other treatments.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Flinders Medical Centre
RECRUITINGBedford Park, South Australia, 5042, Australia
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Fred Hutchinson Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
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Henry Ford Cancer - Detroit
RECRUITINGDetroit, Michigan, 48282, United States
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Hospital Universitario Quirónsalud Madrid
RECRUITINGMadrid, 28223, Spain
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Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
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Jewish General Hospital
RECRUITINGMontreal, Quebec, H3T 1E2, Canada
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Juravinski Cancer Centre
RECRUITINGHamilton, Ontario, L8V 5C2, Canada
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Kinghorn Cancer Centre
RECRUITINGDarlinghurst, New South Wales, 2010, Australia
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Linear Clinical Research
RECRUITINGNedlands, Western Australia, 6009, Australia
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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NEXT Oncology
RECRUITINGFairfax, Virginia, 22031, United States
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Northwest Medical Specialties
RECRUITINGTacoma, Washington, 98405, United States
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Norwalk Hospital
RECRUITINGNorwalk, Connecticut, 06850, United States
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O'Neal Comprehensive Cancer Center at UAB
RECRUITINGBirmingham, Alabama, 35233, United States
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OSF Saint Francis Medical Center
RECRUITINGPeoria, Illinois, 61603, United States
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Oncology Consultants Texas Medical Center
RECRUITINGHouston, Texas, 77030, United States
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Peninsula & South Eastern Hematology and Oncology Group (PAS)
RECRUITINGFrankston, Victoria, 3199, Australia
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Perlmutter Cancer Center - NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Peter MacCallum Cancer Centre
RECRUITINGMelbourne, Victoria, 3051, Australia
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14263, United States
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SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
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The Princess Margaret Cancer Centre
RECRUITINGToronto, Ontario, M5G 2C4, Canada
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The Queen Elizabeth Hospital
RECRUITINGWoodville South, South Australia, 5011, Australia
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UCLA Health - Santa Monica Cancer Care
RECRUITINGSanta Monica, California, 90404, United States
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USOR - Oncology Associates of Oregon, P.C
RECRUITINGEugene, Oregon, 97401, United States
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USOR - Texas Oncology - (DFW) Waco
RECRUITINGWaco, Texas, 76710, United States
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University of California - San Diego Moores Cancer Center
RECRUITINGLa Jolla, California, 92093, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94158, United States
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University of Colorado Cancer Center
RECRUITINGAurora, Colorado, 80045, United States
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66205, United States
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Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06510, United States
Conditions
Explore the condition pages connected to this study.