New stroke drug BB-031 enters human testing

NCT ID NCT06226805

Recruiting now Disease control Sponsor: Basking Biosciences, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new drug called BB-031 in people who have had a stroke within the last 24 hours. About 228 participants will receive either the drug or a placebo, and researchers will check for safety, side effects, and how the drug works in the body over 90 days. The main goal is to see if the drug causes bleeding in the brain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BB-031 (also called DTRI-031), a drug given as an injection
What this could lead to: If it works, this could point toward a new treatment to improve outcomes after a stroke by reducing damage.
What could go wrong: This is an early Phase 2 trial with only 228 participants, so results may not apply to everyone. The drug could cause bleeding in the brain or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Intracranial Hemorrhages ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE

Contacts and locations

Locations

Baptist Health Medical Center
TERMINATED

Jacksonville, Florida, 32207, United States
California Pacific Medical Center
WITHDRAWN

San Francisco, California, 94109, United States
Cooper University Hospital
RECRUITING

Camden, New Jersey, 08103, United States
Fiona Stanley Hospital
RECRUITING

Murdoch, Western Australia, 6150, Australia
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
HonorHealth Bob Bove Neuroscience Institute
RECRUITING

Scottsdale, Arizona, 85251, United States
John Hunter Hospital
RECRUITING

New Lambton Heights, New South Wales, 2305, Australia
Memorial Hermann Hospital
RECRUITING

Houston, Texas, 77030, United States
MemorialCare Long Beach Medical Center
WITHDRAWN

Long Beach, California, 90806, United States
Mercy Health St. Vincent Medical Center
RECRUITING

Toledo, Ohio, 43608, United States
Mills Peninsula Medical Center
WITHDRAWN

Burlingame, California, 94010, United States
Monash Medical Centre
RECRUITING

Clayton, Victoria, 3168, Australia
Ottawa Hospital Research Institute
RECRUITING

Ottawa, Ontario, K1Y 4E9, Canada
Pacific Neurosciences Institute at Saint John's Physician Partners
RECRUITING

Torrance, California, 90503, United States
Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, 4102, Australia
ProMedica Toledo Hospital
RECRUITING

Toledo, Ohio, 43604, United States
Royal Adelaide Hospital
RECRUITING

Adelaide, South Australia, 5000, Australia
The Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
The Royal Melbourne Hospital
RECRUITING

Parkville, Victoria, 3050, Australia
University of Alberta Hospital
RECRUITING

Edmonton, Alberta, T6G 2G3, Canada
University of Calgary
RECRUITING

Calgary, Alberta, T2N2T9, Canada
Valley Baptist Medical Center - Harlingen
RECRUITING

Harlingen, Texas, 78550, United States
Vancouver Stroke Program
RECRUITING

Vancouver, British Columbia, V5Z1M9, Canada
WakeMed
RECRUITING

Raleigh, North Carolina, 27610, United States
Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63110, United States

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