New drug delivers radiation directly to liver cancer cells in first human trial

NCT ID NCT06764316

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 28 times

Summary

This early-stage study tests a new drug, BAY 3547926, that delivers a small amount of radiation directly to liver cancer cells. It is for people with advanced hepatocellular carcinoma (HCC) that has a specific protein called GPC3. The goal is to find a safe dose and see if the drug can shrink tumors, either alone or with other treatments. About 148 participants will take part in this first-in-human study.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Edegem

    RECRUITING

    Edegem, 2650, Belgium

  • Glasgow

    RECRUITING

    Glasgow, Scotland, G12 0YN, United Kingdom

  • Kortrijk

    RECRUITING

    Kortrijk, 8500, Belgium

  • Leuven

    RECRUITING

    Leuven, 3000, Belgium

  • London

    RECRUITING

    London, Greater London, W12 0HS, United Kingdom

  • Madrid

    RECRUITING

    Madrid, 28050, Spain

  • Montreal

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

  • Montréal

    RECRUITING

    Montreal, Quebec, H2X 0C1, Canada

  • Sherbrooke

    RECRUITING

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Sutton

    RECRUITING

    Sutton, Surrey, SM2 5PT, United Kingdom

  • Tampere

    RECRUITING

    Tampere, Pirkanmaa, 33520, Finland

  • Toronto

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

  • Turku

    RECRUITING

    Turku, Southwest Finland, 20540, Finland

Conditions

Explore the condition pages connected to this study.