New pill hopes to boost immune system against tough cancers

NCT ID NCT05614102

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 34 times

Summary

This early-stage study tests a new drug, BAY 2965501, that aims to activate the body's immune T-cells to fight advanced solid tumors (like certain skin, kidney, stomach, and lung cancers). The study involves about 284 participants and will test the drug alone or combined with other treatments. The main goals are to check safety, find the best dose, and see how the drug moves through the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Antwerp University Hospital | Oncology Department

    Antwerp, 2650, Belgium

  • Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center

    Shenzhen, 518172, China

  • Cancer Hospital, Chinese Academy of Medical Sciences

    Beijing, 100000, China

  • Clinica Universidad De Navarra | Madrid | Oncologia

    Madrid, 28027, Spain

  • Clinica Universidad De Navarra | Pamplona | Oncologia

    Pamplona, Madrid, 31008, Spain

  • Freeman Hospital

    Newcastle upon Tyne, Tyne and Wear, NE7 7DN, United Kingdom

  • Ghent University Hospital | Drug Research Unit Department

    Ghent, 9000, Belgium

  • Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital

    London, Greater London, SE1 9RT, United Kingdom

  • Hospital Hm Nou Delfos | Oncologia

    Barcelona, 08023, Spain

  • Hospital Universitari Vall D Hebron | Oncologia

    Barcelona, 08035, Spain

  • Hospital Universitario Hm Sanchinarro | Oncologia

    Madrid, 28050, Spain

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • Oxford University Hospitals NHS Foundation Trust | Churchill Hospital - Oncology

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

  • Royal Marsden NHS Trust (Surrey)

    Sutton, Surrey, SM2 5PT, United Kingdom

  • START | San Antonio

    San Antonio, Texas, 78229, United States

  • Samsung Medical Center - Oncology Department

    Seoul, 135-710, South Korea

  • Sarah Cannon Research Institute at HCA HealthONE Presbyterian St. Luke's

    Denver, Colorado, 80218, United States

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggido, 13620, South Korea

  • Severance Hospital, Yonsei University Health System - Oncology Department

    Seoul, Seoul Teugbyeolsi, 03722, South Korea

  • Sir Run Run Shaw Hospital, Zhejiang Univ. School of Medicine - Oncology Department

    Hangzhou, Zhejiang, 310016, China

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

Explore the condition pages connected to this study.