New drug shows promise for stubborn high blood pressure

NCT ID NCT06034743

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study tested whether a new drug called baxdrostat could help lower blood pressure in people whose high blood pressure wasn't controlled despite taking two or more medications. About 800 adults took either baxdrostat or a placebo pill daily for 12 weeks while continuing their regular blood pressure medications. Researchers measured whether baxdrostat safely lowered blood pressure more effectively than the placebo.

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Locations

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Saraland, Alabama, 36571, United States
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Scottsdale, Arizona, 85054, United States
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Sun City West, Arizona, 85375, United States
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Surprise, Arizona, 85374, United States
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Little Rock, Arkansas, 72211, United States
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Fresno, California, 93720, United States
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Lincoln, California, 95648, United States
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Orange, California, 92868, United States
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Rancho Cucamonga, California, 91730, United States
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Stanford, California, 94304, United States
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New Haven, Connecticut, 06510, United States
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Clearwater, Florida, 33765, United States
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Jacksonville, Florida, 32204, United States
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Port Orange, Florida, 32127, United States
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Atlanta, Georgia, 30344, United States
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Decatur, Georgia, 30033, United States
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Springfield, Illinois, 62702, United States
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Munster, Indiana, 46321, United States
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Lexington, Kentucky, 40503, United States
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Detroit, Michigan, 48202, United States
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Rochester, Minnesota, 55905, United States
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Olive Branch, Mississippi, 38654, United States
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Kansas City, Missouri, 64111, United States
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Kansas City, Missouri, 64128, United States
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Kansas City, Missouri, 64151, United States
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Rosedale, New York, 11422, United States
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The Bronx, New York, 10455, United States
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Chapel Hill, North Carolina, 27599, United States
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New Bern, North Carolina, 28562, United States
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Toledo, Ohio, 43614, United States
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Grants Pass, Oregon, 97527, United States
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Bethlehem, Pennsylvania, 18017, United States
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Langhorne, Pennsylvania, 19047, United States
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East Providence, Rhode Island, 02914, United States
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Memphis, Tennessee, 38105, United States
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Brownsville, Texas, 78526, United States
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Corpus Christi, Texas, 78404, United States
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Houston, Texas, 77054, United States
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Sugar Land, Texas, 77479, United States
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Manassas, Virginia, 20110, United States
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Suffolk, Virginia, 23435, United States
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Madison, Wisconsin, 53792, United States
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Milwaukee, Wisconsin, 53295, United States
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CABA, C1119ACN, Argentina
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CABA, C1425AGC, Argentina
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Ciudad de Buenos Aires, AR-CP 1221, Argentina
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Córdoba, 5000, Argentina
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Córdoba, X5003DCP, Argentina
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Mar del Plata, B7600, Argentina
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Mendoza, M5500, Argentina
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Rosario, S2000PBJ, Argentina
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San Miguel de Tucumán, 4000, Argentina
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San Nicolás, B2900DMH, Argentina
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San Vicente, 5006, Argentina
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Clayton, 3168, Australia
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Darlinghurst, 2010, Australia
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Epping, 3076, Australia
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Geelong, 3220, Australia
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Liverpool, 2170, Australia
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New Lambton Heights, 2305, Australia
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Perth, 6000, Australia
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Wollongong, 2500, Australia
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Woolloongabba, 4102, Australia
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Braunau am Inn, 5280, Austria
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Sankt Pölten, 3100, Austria
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Vienna, 1090, Austria
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Ghent, 9000, Belgium
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Liège, 4000, Belgium
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Mons, 7000, Belgium
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Pleven, 5800, Bulgaria
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Sofia, 1527, Bulgaria
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Sofia, 1618, Bulgaria
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Sofia, 1680, Bulgaria
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Sofia, 1709, Bulgaria
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Edmonton, Alberta, T6G 2C8, Canada
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North Vancouver, British Columbia, V7M 2H4, Canada
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Cambridge, Ontario, N1R 6V6, Canada
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Markham, Ontario, L3S 0A2, Canada
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Newmarket, Ontario, L3Y 2P6, Canada
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Ottawa, Ontario, K1H 7W9, Canada
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Scarborough Village, Ontario, M1B 4Z8, Canada
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Toronto, Ontario, M6G 1M2, Canada
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Waterloo, Ontario, N2T 0C1, Canada
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Chicoutimi, Quebec, G7H 7K9, Canada
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Saint-Jean-sur-Richelieu, Quebec, J3A 1J2, Canada
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Benešov, 256 01, Czechia
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Brandýs nad Labem, 250 01, Czechia
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Broumov, 55001, Czechia
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Louny, 440 01, Czechia
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Ostrava, 708 52, Czechia
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Příbram, 261 01, Czechia
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Uherské Hradiště, 68601, Czechia
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Aarhus, 8200, Denmark
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Herning, 7400, Denmark
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Holbæk, 4300, Denmark
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Bobigny, 93000, France
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Bordeaux, 33076, France
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Paris, 75013, France
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Paris, 75015, France
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Saint-Priest-en-Jarez, 42270, France
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Toulon, 83100, France
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Toulouse, 31059, France
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Tours, 37044, France
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Bad Homburg, 61348, Germany
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Bad Oeynhausen, 32545, Germany
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Berlin, 12203, Germany
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Berlin, 13347, Germany
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Dortmund, 44137, Germany
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Düsseldorf, 40225, Germany
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Elsterwerda, 04910, Germany
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Erlangen, 91054, Germany
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Essen, 45355, Germany
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Frankfurt, 60590, Germany
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Frankfurt, 60596, Germany
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Hanover, 30449, Germany
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Hanover, 30625, Germany
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Homburg, 66424, Germany
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Kaiserslautern, 67655, Germany
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Leipzig, 04103, Germany
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Mannheim, 68167, Germany
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Wermsdorf, 04779, Germany
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Balatonfüred, 8230, Hungary
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Budapest, 1115, Hungary
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Kalocsa, 6300, Hungary
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Kaposvár, 7400, Hungary
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Nyíregyháza, 4400, Hungary
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Pécs, 7623, Hungary
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Delhi, 110029, India
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Delhi, 110060, India
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Guntur, 522001, India
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Kanpur, 208002, India
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Kolkata, 700014, India
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Kolkata, 700020, India
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Mysuru, 570004, India
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Mysuru, 570015, India
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New Delhi, 110002, India
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New Delhi, 110017, India
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Surat, 395001, India
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Ashdod, 7747629, Israel
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Haifa, 3109601, Israel
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Petah Tikva, 49100, Israel
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Ramat Gan, 52621, Israel
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Rehovot, 76100, Israel
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Acquaviva delle Fonti, 70021, Italy
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Bologna, 40138, Italy
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Brescia, 25123, Italy
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Milan, 20122, Italy
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Milan, 20138, Italy
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Milan, 20149, Italy
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Pisa, 56126, Italy
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Roma, 00189, Italy
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Torino, 10126, Italy
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Udine, 33100, Italy
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Adachi-ku, 121-0815, Japan
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Chūōku, 103-0027, Japan
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Chūōku, 260-0804, Japan
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Kanazawa, 920-8530, Japan
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Koga-shi, 306-0232, Japan
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Kyoto, 607-8062, Japan
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Nagasaki, 850-8555, Japan
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Okayama, 700-0804, Japan
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Osaka, 559-0012, Japan
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Sapporo, 003-0026, Japan
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Tsuchiura-shi, 300-0062, Japan
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Yufu-shi, 879-5593, Japan
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Kajang, 43000, Malaysia
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Kota Bharu, 15586, Malaysia
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Kuching, 93586, Malaysia
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Malacca, 75400, Malaysia
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Muar town, 84000, Malaysia
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Sarawak Miri, 98000, Malaysia
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Seri Manjung, 32040, Malaysia
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Hoogeveen, 7909 AA, Netherlands
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Nijmegen, 6525 GA, Netherlands
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Utrecht, 3508 AB, Netherlands
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Bialystok, 15-540, Poland
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Bydgoszcz, 85-095, Poland
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Chrzanów, 32-500, Poland
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Gdansk, 80-214, Poland
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Gdynia, 81-338, Poland
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Krakow, 30-688, Poland
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Lodz, 91-002, Poland
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Poznan, 61-848, Poland
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Warsaw, 02-172, Poland
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Warsaw, 02-758, Poland
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Warsaw, 04-628, Poland
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Brezno, 977 01, Slovakia
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Košice, 04022, Slovakia
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Moldava nad Bodvou, 04501, Slovakia
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Prešov, 080 01, Slovakia
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Rimavská Sobota, 979 01, Slovakia
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Svidník, 08901, Slovakia
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Cape Town, 7500, South Africa
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Centurion, 0157, South Africa
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Claremont, 7708, South Africa
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Durban, 4001, South Africa
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Kwadwesi, 6201, South Africa
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Somerset West, 7130, South Africa
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Worcester, 6850, South Africa
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Bucheon-si, 420-717, South Korea
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Busan, 49241, South Korea
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Daejeon, 35015, South Korea
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Incheon, 21565, South Korea
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Seoul, 02841, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 04763, South Korea
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Seoul, 05505, South Korea
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Seoul, 07441, South Korea
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Seoul, 07804, South Korea
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Seoul, 08308, South Korea
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Barcelona, 08003, Spain
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Barcelona, 08036, Spain
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Ferrol, 15405, Spain
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Granada, 18014, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Majadahonda, 28222, Spain
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Seville, 41004, Spain
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Terrassa (Barcelona), 08221, Spain
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Gothenburg, 413 45, Sweden
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Uppsala, 75185, Sweden
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Kaohsiung City, 80756, Taiwan
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Kaohsiung City, 81362, Taiwan
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Taichung, 40201, Taiwan
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Taichung, 40447, Taiwan
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Taichung, 433004, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 110, Taiwan
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Taipei, 11217, Taiwan
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Yung Kang City, 71044, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10400, Thailand
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Bangkok, 10700, Thailand
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Chiang Mai, 50200, Thailand
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Hat Yai, 90110, Thailand
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Khon Kaen, 40002, Thailand
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Pathum Thani, 12120, Thailand
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Adana, 01060, Turkey (Türkiye)
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Ankara, 06530, Turkey (Türkiye)
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Bursa, 16059, Turkey (Türkiye)
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Dinar, 03400, Turkey (Türkiye)
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Istanbul, 34862, Turkey (Türkiye)
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Izmir, Turkey (Türkiye)
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Kütahya, 43100, Turkey (Türkiye)
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Odunpazari, 26080, Turkey (Türkiye)
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Bollington, SK10 5JH, United Kingdom
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Bristol, BS34 6BQ, United Kingdom
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Chesterfield, S40 4AA, United Kingdom
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Dundee, DD1 9SY, United Kingdom
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Glasgow, G51 4TF, United Kingdom
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Harrow, HA3 7LT, United Kingdom
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Hownslow, TW3 3LN, United Kingdom
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London, EC1M 6BQ, United Kingdom
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London, W6 7HY, United Kingdom
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Prescot, L35 5DR, United Kingdom
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Weston-super-Mare, BS24 7PR, United Kingdom
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Yate, BS37 4AX, United Kingdom
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Da Nang, 550000, Vietnam
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Ho Chi Minh City, 70000, Vietnam
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Hochiminh City, 700000, Vietnam

Conditions

Explore the condition pages connected to this study.

RESISTANT HYPERTENSION UNCONTROLLED HYPERTENSION