Massive study seeks genetic roots of common heart valve condition
NCT ID NCT01980797
First seen Apr 03, 2026 · Last updated May 16, 2026 · Updated 8 times
Summary
This study aims to find the genetic causes of bicuspid aortic valve disease, a common heart defect present at birth. Researchers are gathering data from over 6,400 patients aged 8 and older to understand why some develop serious complications like aortic aneurysms. No treatments or interventions are being tested; the goal is purely to learn more about the disease.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston Medical Center
Boston, Massachusetts, 02218, United States
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Hospital Vall d'Hebron
Barcelona, 08035, Spain
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Istituto Policlinico San Donato
San Donato Milanese, Milan, 20097, Italy
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Laval University
Québec, Quebec, G1V 4G5, Canada
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Monaldi Hospital
Naples, 80100, Italy
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Second University of Naples
Naples, 80131, Italy
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Tufts Medical Center
Boston, Massachusetts, 02111, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Oxford
Oxford, OX3 9DU, United Kingdom
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University of Salerno
Salerno, 36-83023, Italy
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University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
Conditions
Explore the condition pages connected to this study.