Can an arthritis drug shrink hidden HIV reservoirs?

NCT ID NCT07028385

First seen Dec 16, 2025 · Last updated May 18, 2026 · Updated 22 times

Summary

This study tests whether baricitinib, a drug used for arthritis, can safely reduce the hidden HIV reservoirs in people whose HIV is already well-controlled with standard medication. Thirty adults with suppressed HIV will take either baricitinib or a placebo daily for 12 weeks while continuing their regular HIV treatment. The goal is to see if baricitinib can help shrink the virus's hiding places, potentially leading to better long-term control.

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Contacts and locations

Locations

  • Fundació Lluita contra les Infeccions - Hospital Universitari Germans Trias i Pujol

    Badalona, Barcelona, 08916, Spain

Conditions

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