Pill shows promise for regrowing hair in major alopecia trial

NCT ID NCT03570749

Completed Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

Summary

This study tested whether baricitinib, a pill taken daily, could help regrow hair in adults with severe alopecia areata, an autoimmune condition causing significant hair loss. Over 760 participants were randomly assigned to receive either a low dose, a high dose, or a placebo pill to compare effectiveness and safety. The main goal was to see if the treatment could reduce scalp hair loss to 20% or less, and it also measured regrowth of eyebrows and eyelashes, as well as impacts on anxiety and depression.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

ActivMed Practices and Research

Beverly, Massachusetts, 01915, United States
ActivMed Practices and Research

Portsmouth, New Hampshire, 03801, United States
Alliance Research Centers

Irvine, California, 92612, United States
Austin Institute for Clinical Research

Pflugerville, Texas, 78660, United States
B&B Investigaciones Medicas, SC

Mazatlán, Sinaloa, 82140, Mexico
Bellaire Dermatology

Bellaire, Texas, 77401, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
CRI Centro Regiomontano de Investigacion S.C.

Monterrey, Nuevo León, 64060, Mexico
California Dermatology & Clinical Research Institute

Encinitas, California, 92024, United States
Callender Center for Clinical Research, LLC / Research

Glenn Dale, Maryland, 20769, United States
Center for Clinical Studies

Houston, Texas, 77004, United States
Center for Clinical Studies

Webster, Texas, 77598, United States
Chonbuk National University Hospital

Jeonju, Jeon Ra Buk-Do, Korea, 54907, South Korea
Chungang University Hospital

Seoul, 06973, South Korea
Chungnam National University Hospital

Daejeon, Korea, 35015, South Korea
Clarkston Skin Research

Clarkston, Michigan, 48346, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Clinica de Investigacion en Reumatologia y Obesidad S. C.

Guadalajara, Jalisco, 44650, Mexico
Coastal Clinical Research, Inc

Mobile, Alabama, 36608, United States
Consultorio Privado de la Dra. Villanueva

Guadalajara, Jalisco, 44657, Mexico
Derma Norte del Bajío, S.C.

Aguascalientes, Mexico
Dermatology Associates

Seattle, Washington, 98101, United States
Dermatology Associates of Plymouth Meeting

Plymouth Meeting, Pennsylvania, 19462, United States
Dermatology Clinical Research Center of San Antonio

San Antonio, Texas, 78229, United States
Dermatology Research Associates

Los Angeles, California, 90045, United States
Dermatology and Skin Surgery Center

Exton, Pennsylvania, 19341, United States
Eunpyeong St. Mary's Hospital

Seoul, 03312, South Korea
ForCare Clinical Research

Tampa, Florida, 33613-1244, United States
Forefront Research

Louisville, Kentucky, 40241, United States
GCM Medical Group, PSC- Hato Rey

San Juan, PR, 00917, Puerto Rico
Hamamatsu University School of Medicine, University Hospital

Hamamatsu, Shizuoka, 431-3192, Japan
Hospital Universitario Dr. Jose Eleuterio Gonzalez

Monterrey, N.L., 64460, Mexico
Inha University Hospital

Jung-gu, Incheon, 22332, South Korea
Instituto de Investigaciones Aplicadas a la Neurociencia A.C

Durango, 34000, Mexico
Johnson Dermatology

Fort Smith, Arkansas, 72916, United States
Konkuk University Medical Center

Seoul, 05030, South Korea
Kurume University Hospital

Kurume, Fukuoka, 830 0011, Japan
Kyung Pook National University Hospital

Daegu, Korea, 41944, South Korea
Kyunghee University Hospital at Gangdong

Seoul, 05278, South Korea
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Medaphase Inc

Newnan, Georgia, 30263, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Modern Research Associates

Dallas, Texas, 75231, United States
Montefiore Medical Center

The Bronx, New York, 10467-2490, United States
Mosaic Dermatology

Santa Monica, California, 90403, United States
NW Dermatology & Research Center, LLC

Portland, Oregon, 97210, United States
Northwestern University

Chicago, Illinois, 60611, United States
OH State Univ College of Med

Gahanna, Ohio, 43230, United States
OHSU Center for Health and Healing

Portland, Oregon, 97239, United States
Oregon Medical Research Center

Portland, Oregon, 97223, United States
Osaka City University Hospital

Osaka, 545-8586, Japan
Park Avenue Dermatology

Orange Park, Florida, 32073, United States
Penn State Univ. Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Perelman Center for Advanced Medicine

Philadelphia, Pennsylvania, 19104, United States
Ponce School of Medicine CAIMED Center

Ponce, PR, 00716, Puerto Rico
Pusan National University Hospital

Busan, Korea, 49241, South Korea
RM Pharma Specialists S.A. de C.V.

Distrito Federal, 3100, Mexico
Seoul National University Bundang Hospital

Seongnam, Geonggi-do, 13620, South Korea
Seoul National University Hospital

Seoul, 03080, South Korea
Skin Care Physicians of Georgia

Macon, Georgia, 31217, United States
Solutions Through Advanced Research, Inc.

Jacksonville, Florida, 32256, United States
Stanford Health Care

Redwood City, California, 94063, United States
Texas Dermatology and Laser Specialists

San Antonio, Texas, 78218, United States
Tokyo Medical Univ. Hospital

Shinjuku-ku, Tokyo, 160-0023, Japan
University Clinical Trials, Inc.

San Diego, California, 92123, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35233, United States
University of CA, Irvine

Irvine, California, 92617, United States
University of California Davis-Dermatology

Sacramento, California, 95816, United States
University of Miami

Miami, Florida, 33125, United States
University of Minnesota Medical School

Minneapolis, Minnesota, 55455, United States
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States
University of Rochester School of Medicine

Rochester, New York, 14642, United States
University of Utah MidValley Dematology

Murray, Utah, 84107, United States
Yale University School of Medicine

New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.

ALOPECIA AREATA