New drug combo shows promise for rare childhood muscle disease
NCT ID NCT05524311
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the drug baricitinib, given with steroids, in 16 children aged 3-18 with newly diagnosed juvenile dermatomyositis, a rare disease causing muscle weakness and skin rashes. The goal was to see if baricitinib works better than the standard treatment (methotrexate plus steroids) at improving muscle strength and daily activities over 24 weeks. The approach aims to control the disease with a good safety profile, but ongoing management is still needed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hopital Necker - Enfants malades : unité d'immuno-hématologie et rhumatologie
Paris, France
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Hôpital Brabois
Nancy, France
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Hôpital Femme Mère Enfant
Bron, France
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Hôpital Jeanne de Flandre
Lille, France
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Hôpital La Timone
Marseille, France
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Hôpital Necker - Enfants malades : service de dermatologie
Paris, France
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Hôpital Pellegrin
Bordeaux, France
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Hôpital Purpan
Toulouse, France
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Hôpital Robert Debré
Paris, France
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Hôpital Trousseau
Paris, France
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Hôpital Villeneuce
Montpellier, France
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Hôpital de Hautepierre
Strasbourg, France
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Hôpital du Kremlin-Bicêtre
Paris, France