New hope for kids with rare muscle disease: experimental drug trial shows promise

NCT ID NCT05524311

Summary

This study tested whether adding the drug baricitinib to standard steroid treatment works better for children newly diagnosed with juvenile dermatomyositis, a rare and serious autoimmune disease that causes muscle weakness and skin rashes. Sixteen children aged 3-18 participated in this 24-week trial, comparing the new combination to the usual treatment of steroids plus methotrexate. The goal was to see if baricitinib could more effectively control the disease, especially in its severe forms, with an acceptable safety profile.

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Contacts and locations

Locations

  • Hopital Necker - Enfants malades : unité d'immuno-hématologie et rhumatologie

    Paris, France

  • Hôpital Brabois

    Nancy, France

  • Hôpital Femme Mère Enfant

    Bron, France

  • Hôpital Jeanne de Flandre

    Lille, France

  • Hôpital La Timone

    Marseille, France

  • Hôpital Necker - Enfants malades : service de dermatologie

    Paris, France

  • Hôpital Pellegrin

    Bordeaux, France

  • Hôpital Purpan

    Toulouse, France

  • Hôpital Robert Debré

    Paris, France

  • Hôpital Trousseau

    Paris, France

  • Hôpital Villeneuce

    Montpellier, France

  • Hôpital de Hautepierre

    Strasbourg, France

  • Hôpital du Kremlin-Bicêtre

    Paris, France

Conditions

Explore the condition pages connected to this study.