New drug combo shows promise for rare childhood muscle disease
NCT ID NCT05524311
First seen Nov 20, 2025 · Last updated May 15, 2026 · Updated 20 times
Summary
This study tested whether baricitinib, a drug that calms the immune system, works better than standard treatment when combined with steroids for children aged 3 to 18 with newly diagnosed juvenile dermatomyositis, a rare disease causing muscle weakness and rash. Sixteen children took part over 24 weeks. The goal was to see if at least 20% improvement in muscle strength, daily function, and quality of life could be achieved safely.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hopital Necker - Enfants malades : unité d'immuno-hématologie et rhumatologie
Paris, France
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Hôpital Brabois
Nancy, France
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Hôpital Femme Mère Enfant
Bron, France
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Hôpital Jeanne de Flandre
Lille, France
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Hôpital La Timone
Marseille, France
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Hôpital Necker - Enfants malades : service de dermatologie
Paris, France
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Hôpital Pellegrin
Bordeaux, France
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Hôpital Purpan
Toulouse, France
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Hôpital Robert Debré
Paris, France
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Hôpital Trousseau
Paris, France
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Hôpital Villeneuce
Montpellier, France
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Hôpital de Hautepierre
Strasbourg, France
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Hôpital du Kremlin-Bicêtre
Paris, France
Conditions
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