New study tests if barbed sutures can prevent Post-Hysterectomy complications
NCT ID NCT05833204
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of sutures used to close the vaginal cuff after laparoscopic hysterectomy: barbed absorbable sutures versus standard absorbable sutures. The goal is to see if barbed sutures reduce the risk of vaginal cuff separation and other complications. Over 1,600 women undergoing hysterectomy for non-cancer reasons will be randomly assigned to one suture type and followed for outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- barbed absorbable suture (V-Loc) vs standard absorbable suture (Vicryl)
- What this could lead to
- If barbed sutures prove better, this could reduce serious complications like vaginal cuff separation after hysterectomy, improving recovery for many women.
- What could go wrong
- This is a large but early-stage trial; previous studies were small or retrospective, so results may not confirm a clear benefit. Risks include infection or suture-related issues.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AOUI Verona - University of Verona - Department of Obstetrics and Gynecology
Verona, 37125, Italy
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