New study tests if barbed sutures can prevent Post-Hysterectomy complications

NCT ID NCT05833204

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of sutures used to close the vaginal cuff after laparoscopic hysterectomy: barbed absorbable sutures versus standard absorbable sutures. The goal is to see if barbed sutures reduce the risk of vaginal cuff separation and other complications. Over 1,600 women undergoing hysterectomy for non-cancer reasons will be randomly assigned to one suture type and followed for outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

barbed absorbable suture (V-Loc) vs standard absorbable suture (Vicryl)

What this could lead to

If barbed sutures prove better, this could reduce serious complications like vaginal cuff separation after hysterectomy, improving recovery for many women.

What could go wrong

This is a large but early-stage trial; previous studies were small or retrospective, so results may not confirm a clear benefit. Risks include infection or suture-related issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AOUI Verona - University of Verona - Department of Obstetrics and Gynecology

    Verona, 37125, Italy