Can exercise rewire the brain in people with movement disorders?
NCT ID NCT05002218
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether balance training or aerobic cycling can improve movement and brain function in 64 people with cerebellar ataxia, a condition that affects coordination. Participants did one type of exercise five times a week for 30 minutes. Researchers used brain scans to see how each exercise affects the brain. The goal is to find which type of training helps more and why.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- balance training and aerobic training on a stationary bike
- What this could lead to
- If it works, this could point toward better exercise-based therapies to improve walking and coordination in people with cerebellar ataxia.
- What could go wrong
- This is a small, early-stage study (64 people) that looks at brain changes, not a proven treatment. Results may not apply to everyone with ataxia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Columbia University Irving Medical Center
New York, New York, 10032, United States
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